Transplacental antibody transfer from mother to fetus provides protection from infection in
the first weeks of life, and the four different subclasses of IgG (IgG1, IgG2, IgG3, and IgG4) …

Background Infants< 3 months of age are at highest risk for developing severe complications
after pertussis. The majority of pregnant women has low concentrations of pertussis-specific …

Introduction Infants too young to be fully immunized are the most vulnerable to severe
pertussis disease. To close this susceptibility gap, passive infant immunization through …

Immunizing pregnant women to protect the mother, fetus and infant from infection has
increasingly been used over the last decade. Protection against infectious diseases in …

Pertussis is a highly communicable acute respiratory infection caused by Bordetella
pertussis. Immunity is not lifelong after natural infection or vaccination. Pertussis outbreaks …

Vaccinating women in pregnancy (ie, maternal immunization) has emerged as a promising
tool to tackle infant morbidity and mortality worldwide. This approach nurtures a 'gift of …

Background Immunisation is an important public health policy and measuring coverage is
imperative to identify gaps and monitor trends. New Zealand (NZ), like many countries, does …

Background Pertussis immunization during pregnancy results in high pertussis antibody
concentrations in young infants but may interfere with infant immune responses to post-natal …

Live-attenuated vaccines (LAV) are currently contraindicated during pregnancy, given
uncertain safety records for the mother–infant pair. LAV might, however, play an important …

Despite high vaccine coverage in many parts of the world, pertussis is resurging in a number
of areas in which acellular vaccines are the primary vaccine administered to infants and …