Despite the often seemingly innocuous nature of a mild traumatic brain injury (mTBI), its
consequences can be devastating, comprising debilitating symptoms that interfere with daily …

Background: Mild traumatic brain injury (mTBI) is a putative risk factor for dementia;
however, despite having apparent face validity, the evidence supporting this hypothesis …

Objective: Identification and validation of blood-based biomarkers for the diagnosis and
prognosis of mild traumatic brain injury (mTBI) is of critical importance. There have been …

Traumatic brain injury (TBI) increases the risk of delayed neurodegenerative processes,
including Parkinson's disease (PD). Interleukin-1beta (IL-1β), a key pro-inflammatory …

Background Serum glial fibrillary acidic protein (GFAP) and ubiquitin carboxyl-terminal
esterase L1 (UCH-L1) have recently received US Food and Drug Administration approval for …

Mild traumatic brain injury (mTBI) causes persisting post-concussion syndrome for many
patients without abnormalities on conventional neuroimaging. Currently, there is no method …

Background: Technology platforms that afford biomarker discovery in patients suffering from
traumatic brain injury (TBI) remain an unmet medical need. Here, we describe an …

Traumatic brain injury (TBI) is the leading cause of death and disability in patients with
various types of trauma. Assessing the severity and prognosis of TBI can help to rationally …

Age and severity are significant predictors of traumatic brain injury (TBI) outcomes in the
immature brain. TBI studies have segregated TBI injury into three severity groups: mild …

Technological platforms that enable rapid biomarker detection, disease diagnosis,
prognosis, and treatment monitoring can significantly improve outcomes for patients. This is …