Fragmented or otherwise miniaturized plastic materials in the form of micro-or nanoplastics
have been of nagging environmental concern. Perturbation of organismal physiology and …

Platelets are chief cells in hemostasis. Apart from their hemostatic roles, platelets are major
inflammatory effector cells that can influence both innate and adaptive immune responses …

Cardiovascular disease and infections are major causes for the high incidence of morbidity
and mortality of patients with chronic kidney disease. Both complications are directly or …

Acute myeloid leukemia (AML) is a heterogeneous disease caused by several gene
mutations and cytogenetic abnormalities affecting differentiation and proliferation of myeloid …

Introduction: A recent study showed that early renal tubular injury is ameliorated in Nod-like
receptor pyrin domain-containing protein 3 (NLRP3) KO mice with rhabdomyolysis-induced …

Inflammasome complex is a multimeric protein comprising of upstream sensor protein of
nucleotide-binding oligomerization domain (NOD)-like receptor family. It has an adaptor …

Background: Myxomatous valve degeneration (MVD) involves the progressive thickening
and degeneration of the heart valves, leading to valve prolapse, regurgitant blood flow, and …

Because of their highly reactive nature and potentially toxic characteristic, reactive oxygen
species (ROS) have had a bad reputation for years. However, under certain conditions, ROS …

Atherosclerosis (ATH) is a chronic, dynamic, evolutive process involving morphological and
structural subversion of artery walls, leading to the formation of atherosclerotic plaques. ATH …

The pathways for peripheral-to-central immune communication (P→ C I-comm) following
sterile lung injury (SLI) are unknown. SLI evokes systemic and central inflammation, which …