Diverse roles for hyaluronan and hyaluronan receptors in the developing and adult nervous system

A Peters, LS Sherman - International journal of molecular sciences, 2020 - mdpi.com
Hyaluronic acid (HA) plays a vital role in the extracellular matrix of neural tissues. Originally
thought to hydrate tissues and provide mechanical support, it is now clear that HA is also a …

Dysregulation of hyaluronan homeostasis during white matter injury

T Srivastava, LS Sherman, SA Back - Neurochemical research, 2020 - Springer
Although the extra cellular matrix (ECM) comprises a major proportion of the CNS
parenchyma, new roles for the ECM in regeneration and repair responses to CNS injury …

Hyaluronan regulates synapse formation and function in developing neural networks

E Wilson, W Knudson, K Newell-Litwa - Scientific Reports, 2020 - nature.com
Neurodevelopmental disorders present with synaptic alterations that disrupt the balance
between excitatory and inhibitory signaling. For example, hyperexcitability of cortical …

The stemness gene Mex3A is a key regulator of neuroblast proliferation during neurogenesis

V Naef, M De Sarlo, G Testa, D Corsinovi… - Frontiers in cell and …, 2020 - frontiersin.org
Mex3A is an RNA binding protein that can also act as an E3 ubiquitin ligase to control gene
expression at the post-transcriptional level. In intestinal adult stem cells, MEX3A is required …

Neural Crest and the Cornea: Transformation of the Transcriptome and the Role of Nephronectin during Ocular Development

J Ma - 2020 - search.proquest.com
Corneal development is an intricate process that involves signaling and interactions
between the periocular neural crest cells (pNC) s, presumptive corneal epithelium, lens, and …

[PDF][PDF] Increased Hyaluronic Acid Level in Mid-Trimester Amniotic Fluid of Trisomy 21 Fetuses with Hydrops

YL Chang, A Chao, SH You, PJ Cheng - 2020 - scholar.archive.org
Background: Trisomy 21 is the most prevalent chromosomal anomaly among new-borns
with mental disability. The phenotypes with trisomy 21 may involve short stature, mental …