Nucleic acids are gaining significant attention as versatile building blocks for the next
generation of soft materials. Due to significant advances in the chemical synthesis and …

Specific interactions between ligands and receptors on cell surface play an important role in
the cell biological process. Nucleic acid aptamers as commonly used ligands enable …

Stem cells have been widely studied in cell biology and utilized in cell-based therapies, and
fishing stem cells from marrow is highly challenging due to the ultralow content. Herein, a …

The tunability of SELEX procedure is an essential feature to supply bioaffinity receptors
(aptamers) almost on demand for analytical and therapeutic purposes. This longstanding …

The capture and analysis of circulating tumor cells (CTCs) have provided a non‐invasive
entry for cancer diagnosis and disease monitoring. Despite recent development in affinity …

Monitoring circulating tumor cells (CTCs) in human blood can offer useful information for
convenient metastasis diagnosis, prognosis, and treatment of cancers. However, it remains …

Traditional anticancer therapies can cause serious side effects in clinical treatment due to
their nonspecific of tumor cells. Aptamers, also termed as' chemical antibodies', are short …

Multivalency is nature's way to establish firm and specific interactions when the binding sites
of a protein receptor have only low affinity for monovalent ligands. Recently, researchers are …

Circulating tumor cells (CTCs) enable noninvasive liquid biopsy and identification of cancer.
Various approaches exist for the capture and release of CTCs, including microfluidic …

Aptamer based microfluidic platforms have been developed rapidly in recent years, and
strategies to improve detection sensitivities of such platforms have attracted a significant …