Pathophysiology, clinical presentation, and treatment of psoriasis: a review

AW Armstrong, C Read - Jama, 2020 - jamanetwork.com
Importance Approximately 125 million people worldwide have psoriasis. Patients with
psoriasis experience substantial morbidity and increased rates of inflammatory arthritis …

Pan-cancer characterization of immune-related lncRNAs identifies potential oncogenic biomarkers

Y Li, T Jiang, W Zhou, J Li, X Li, Q Wang, X Jin… - Nature …, 2020 - nature.com
Long noncoding RNAs (lncRNAs) are emerging as critical regulators of gene expression
and they play fundamental roles in immune regulation. Here we introduce an integrated …

Association between psoriasis and celiac disease: A systematic review and meta-analysis

P Acharya, M Mathur - Journal of the American Academy of Dermatology, 2020 - Elsevier
Background Multiple studies have examined the association between psoriasis and celiac
disease (CD). However, these studies have shown conflicting results. Objective To analyze …

Impact of having family history of psoriasis or psoriatic arthritis on psoriatic disease

D Solmaz, S Bakirci, G Kimyon, EK Gunal… - Arthritis care & …, 2020 - Wiley Online Library
Objective Psoriatic arthritis (PsA) has a genetic background. Approximately 40% of patients
with psoriasis or PsA have a family history of psoriasis or PsA, which may affect disease …

Skin expression of IL-23 drives the development of psoriasis and psoriatic arthritis in mice

L Chen, M Deshpande, M Grisotto, P Smaldini… - Scientific Reports, 2020 - nature.com
Psoriasis (PS) is a chronic skin inflammation. Up to 30% of the patients with PS develop
psoriatic arthritis (PsA), a condition characterized by inflammatory arthritis that affects joints …

[HTML][HTML] Long non‑coding RNA HCP5 promotes prostate cancer cell proliferation by acting as the sponge of miR‑4656 to modulate CEMIP expression

R Hu, Z Lu - Oncology reports, 2020 - spandidos-publications.com
Aberrant expression of long noncoding RNAs (lncRNAs) has been demonstrated in human
cancers and regulates the malignant behavior of cancer cells. Previous studies …

Identification of new susceptibility loci associated with rheumatoid arthritis

RX Leng, DS Di, J Ni, XX Wu, LL Zhang… - Annals of the …, 2020 - ard.bmj.com
Objectives The present study aimed to discover novel susceptibility loci associated with risk
of rheumatoid arthritis (RA). Methods We performed a new genome-wide association study …

Genetics and the axial spondyloarthritis spectrum

MA Brown, H Xu, Z Li - Rheumatology, 2020 - academic.oup.com
The axial SpAs (axSpAs) are clearly clinically a heterogeneous set of diseases with
markedly varying extra-articular features. These diseases are all highly heritable and have …

The genetics of spondyloarthritis

R Díaz-Peña, P Castro-Santos, J Durán… - Journal of Personalized …, 2020 - mdpi.com
The term spondyloarthritis (SpA) encompasses a group of chronic inflammatory diseases
with common features in terms of clinical presentation and genetic predisposition. SpA is …

High-throughput phenotyping reveals expansive genetic and structural underpinnings of immune variation

L Abeler-Dörner, AG Laing, A Lorenc, DS Ushakov… - Nature …, 2020 - nature.com
By developing a high-density murine immunophenotyping platform compatible with high-
throughput genetic screening, we have established profound contributions of genetics and …