An audit of uncertainty in multi-scale cardiac electrophysiology models

RH Clayton, Y Aboelkassem… - … of the Royal …, 2020 - royalsocietypublishing.org
Models of electrical activation and recovery in cardiac cells and tissue have become
valuable research tools, and are beginning to be used in safety-critical applications …

[HTML][HTML] Mini review: Deep learning for atrial segmentation from late gadolinium-enhanced MRIs

K Jamart, Z Xiong, GD Maso Talou… - Frontiers in …, 2020 - frontiersin.org
Segmentation and 3D reconstruction of the human atria is of crucial importance for precise
diagnosis and treatment of atrial fibrillation, the most common cardiac arrhythmia. However …

A novel electrochemical aptasensor for the sensitive detection of kanamycin based on UiO-66-NH 2/MCA/MWCNT@ rGONR nanocomposites

X Yao, J Shen, Q Liu, H Fa, M Yang, C Hou - Analytical Methods, 2020 - pubs.rsc.org
In this work, we designed and synthesized a nanocomposite comprising an amine-
functionalized metal organic framework (UiO-66-NH2), a multiwalled carbon nanotube …

Optical mapping-validated machine learning improves atrial fibrillation driver detection by multi-electrode mapping

AM Zolotarev, BJ Hansen, EA Ivanova… - Circulation …, 2020 - Am Heart Assoc
Background: Atrial fibrillation (AF) can be maintained by localized intramural reentrant
drivers. However, AF driver detection by clinical surface-only multielectrode mapping (MEM) …

[HTML][HTML] Automatic detection of atrial fibrillation based on CNN-LSTM and shortcut connection

Y Ping, C Chen, L Wu, Y Wang, M Shu - Healthcare, 2020 - mdpi.com
Atrial fibrillation (AF) is one of the most common persistent arrhythmias, which has a close
connection to a large number of cardiovascular diseases. However, if spotted early, the …

Automated classification of atrial fibrillation using artificial neural network for wearable devices

F Ma, J Zhang, W Liang, J Xue - Mathematical Problems in …, 2020 - Wiley Online Library
Atrial fibrillation (AF), as one of the most common arrhythmia diseases in clinic, is a
malignant threat to human health. However, AF is difficult to monitor in real time due to its …

[HTML][HTML] Impaired neuronal sodium channels cause intranodal conduction failure and reentrant arrhythmias in human sinoatrial node

N Li, A Kalyanasundaram, BJ Hansen, EJ Artiga… - Nature …, 2020 - nature.com
Mechanisms for human sinoatrial node (SAN) dysfunction are poorly understood and
whether human SAN excitability requires voltage-gated sodium channels (Nav) remains …

[HTML][HTML] Identifying locations of re-entrant drivers from patient-specific distribution of fibrosis in the left atrium

A Roy, M Varela, H Chubb, R MacLeod… - PLoS computational …, 2020 - journals.plos.org
Clinical evidence suggests a link between fibrosis in the left atrium (LA) and atrial fibrillation
(AF), the most common sustained arrhythmia. Image-derived fibrosis is increasingly used for …

[HTML][HTML] Epicardial fibrosis explains increased endo–epicardial dissociation and epicardial breakthroughs in human atrial fibrillation

A Gharaviri, E Bidar, M Potse, S Zeemering… - Frontiers in …, 2020 - frontiersin.org
Background Atrial fibrillation (AF) is accompanied by progressive epicardial fibrosis,
dissociation of electrical activity between the epicardial layer and the endocardial bundle …

Unmasking arrhythmogenic hubs of reentry driving persistent atrial fibrillation for patient‐specific treatment

BJ Hansen, J Zhao, KM Helfrich, N Li… - Journal of the …, 2020 - Am Heart Assoc
Background Atrial fibrillation (AF) driver mechanisms are obscured to clinical multielectrode
mapping approaches that provide partial, surface‐only visualization of unstable 3 …