Asthma is a clinical syndrome that affects all age groups. Asthma prevalence worldwide has
seen a rapid increase in the latter part of the last century. Recent data has shown that …

Asthma is a complex disease that often starts in childhood. Genomic and environmental
factors as well as aberrant immune maturation early in life can contribute to the onset of …

Importance Severe asthma exacerbations cause significant morbidity and costs. Whether
vitamin D 3 supplementation reduces severe childhood asthma exacerbations is unclear …

The last couple of decades have seen an explosion in our interest and understanding of the
role of vitamin D in the regulation of immunity. At the molecular level, the hormonal form of …

Abstract Purpose of Review Using the WHO Conceptual Framework for Action on the Social
Determinants of Health, this review provides a discussion of recent epidemiologic …

Existing micronutrient deficiencies, even if only a single micronutrient, can impair immune
function and increase susceptibility to infectious disease. Certain population groups are …

Background: Vitamin D supplementation is known to both prevent and treat rickets, a
disease of hypomineralized bone. Childhood is a period of great bone development and …

Evidence is accumulating that vitamin D may have beneficial effects on respiratory tract,
autoimmune, neuro-degenerative, and mental diseases. The present umbrella review of …

Rationale: Vitamin D deficiency is common in patients with asthma and chronic obstructive
pulmonary disease (COPD). Low 25-hydroxyvitamin D (25 [OH] D) levels may represent a …

Background: Vitamin D exerts multiple pleiotropic effects beyond its role in calcium-
phosphate metabolism. Growing evidence suggests an association between …