The rise of antibiotic resistance and declining discovery of new antibiotics has created a
global health crisis. Of particular concern, no new antibiotic classes have been approved for …

Autotransporters are important virulence factors in the outer membrane of gram-negative
bacteria. Although several autotransporters have been identified in Neisseria meningitidis …

Immunity to Neisseria gonorrhoeae has been hard to define because, until recently, there
has been no evident state of immunity to gonorrhea in humans; re-infections are fairly …

Neisseria gonorrhoeae (Ngo) is the bacterial pathogen responsible for the sexually
transmitted infection gonorrhea. Aside from the cervicitis typical of gonococcal infection in …

Pelvic inflammatory disease (PID) is a source of significant morbidity in women and is often
caused by upper reproductive tract infection with the common sexually transmitted …

Untreatable gonorrhea, caused by fully antimicrobial resistant Neisseria gonorrhoeae (GC),
is a major global health threat. While a vaccine would greatly help address this crisis …