Cellular-scale imaging of transparent retinal structures and processes using adaptive optics optical coherence tomography

DT Miller, K Kurokawa - Annual review of vision science, 2020 - annualreviews.org
High-resolution retinal imaging is revolutionizing how scientists and clinicians study the
retina on the cellular scale. Its exquisite sensitivity enables time-lapse optical biopsies that …

Tissue phantoms for biomedical applications in Raman spectroscopy: a review

MZ Vardaki, N Kourkoumelis - Biomedical engineering and …, 2020 - journals.sagepub.com
Raman spectroscopy is a group of analytical techniques, currently applied in several
research fields, including clinical diagnostics. Tissue-mimicking optical phantoms have been …

Monitoring tissue-level remodelling during inflammatory arthritis using a three-dimensional synovium-on-a-chip with non-invasive light scattering biosensing

M Rothbauer, G Höll, C Eilenberger, SRA Kratz… - Lab on a Chip, 2020 - pubs.rsc.org
Rheumatoid arthritis is a chronic, systemic joint disease in which an autoimmune response
translates into an inflammatory attack resulting in joint damage, disability and decreased …

Advanced bioluminescence system for in vivo imaging with brighter and red-shifted light emission

M Endo, T Ozawa - International Journal of Molecular Sciences, 2020 - mdpi.com
In vivo bioluminescence imaging (BLI), which is based on luminescence emitted by the
luciferase–luciferin reaction, has enabled continuous monitoring of various biochemical …

Deep learning-based light scattering microfluidic cytometry for label-free acute lymphocytic leukemia classification

J Sun, L Wang, Q Liu, A Tárnok, X Su - Biomedical Optics Express, 2020 - opg.optica.org
The subtyping of Acute lymphocytic leukemia (ALL) is important for proper treatment
strategies and prognosis. Conventional methods for manual blood and bone marrow testing …

Two‐dimensional light scattering anisotropy cytometry for label‐free classification of ovarian cancer cells via machine learning

X Su, T Yuan, Z Wang, K Song, R Li, C Yuan… - Cytometry Part …, 2020 - Wiley Online Library
We develop a single‐mode fiber‐based cytometer for the obtaining of two‐dimensional (2D)
light scattering patterns from static single cells. Anisotropy of the 2D light scattering patterns …

Evaluation of the optical and biomechanical properties of bioengineered human skin generated with fibrin-agarose biomaterials

AM Ionescu, J Chato-Astrain… - Journal of …, 2020 - spiedigitallibrary.org
Significance: Recent generation of bioengineered human skin allowed the efficient
treatment of patients with severe skin defects. However, the optical and biomechanical …

Scattering angle resolved optical coherence tomography detects early changes in 3xTg Alzheimer's disease mouse model

MR Gardner, V Baruah, G Vargas… - … Vision Science & …, 2020 - tvst.arvojournals.org
Purpose: Clinical intensity-based optical coherence tomographic retinal imaging is unable to
resolve some of the earliest changes to Alzheimer's disease (AD) neurons. The aim of this …

Diffusive optical tomography in the Bayesian framework

K Newton, Q Li, AM Stuart - Multiscale Modeling & Simulation, 2020 - SIAM
Many naturally occurring models in the sciences are well approximated by simplified models
using multiscale techniques. In such settings it is natural to ask about the relationship …

Theoretical determination of two-photon absorption in biologically relevant pterin derivatives

T Malcomson, MJ Paterson - Photochemical & Photobiological Sciences, 2020 - Springer
Given the prevalence of fluorescence spectroscopy in biological systems, and the
prevalence of pterin derivatives throughout biological systems, presented here is an …