Evans' syndrome (ES) is defined as the concomitant or sequential association of warm auto-
immune haemolytic anaemia (AIHA) with immune thrombocytopenia (ITP), and less …

Juvenile myelomonocytic leukaemia (JMML) is a rare clonal disorder of early childhood.
Constitutive activation of the RAS pathway is the initial event in JMML. Around 90% of …

Hematopoietic stem cell transplantation (HSCT) is the only curative treatment for juvenile
myelomonocytic leukemia (JMML), but few large studies of HSCT for JMML exist. Using data …

Background: Juvenile myelomonocytic leukemia (JMML) is a rare myelodysplastic/
myeloproliferative neoplasm diagnosed in young children, characterized by somatic or …

The myelodysplastic/myeloproliferative neoplasms (MDS/MPN) are a heterogenous group of
myeloid malignancies hallmarked by clinicopathologic features that overlap with …

Juvenile myelomonocytic leukemia (JMML) is a heterogeneous childhood leukemia. The
management of patients with JMML requires accurate assessment of genetic and clinical …

骨髓增生异常综合征RAS基因突变的分子学特征及预后意义- PMC Back to Top Skip to main
content NIH NLM Logo Access keys NCBI Homepage MyNCBI Homepage Main Content Main …

Recent studies have reported loss of heterozygosity in the chromosome 6p arms (6pLOH) of
acquired aplastic anemia (AA) patients, and in tumor cells trying to escape the autoimmune …

Patients with juvenile myelomonocytic leukemia due to germline CBL mutation (10% to
15%) may have a subacute course occasionally associated with autoimmune disorders …

Introduction Juvenile myelomonocytic leukemia (JMML) is a rare clonal myelodysplastic/
myeloproliferative neoplasm of early childhood. Historically, it was difficult to diagnose …