Acute lung injury (ALI) and acute kidney injury (AKI) are major causes of sepsis-induced
mortality. The objective of the study is to evaluate the effect of tocilizumab (TCZ), an IL-6 …

Objectives Sepsis is a severe organic dysfunction caused by an infection that affects the
normal regulation of several organ systems, including the central nervous system …

Objectives: Natural medicine has been proposed for treating sepsis worldwide. Therefore, in
this study, the effect of deuterium-depleted water (DDW) alone and adjuvant with Rosa …

Objective: This study was aimed at investigating the regulation of mitochondrial function by
histone deacetylase 6 (HDAC6) and the role of HDAC6 in the development and progression …

Sepsis causes organ dysfunction due to an infection, and it may impact the central nervous
system. Neuroinflammation and oxidative stress are related to brain dysfunction after sepsis …

Recent studies have shown azithromycin-specific clinical efficacy against macrolide-
resistant strains of Streptococcus pneumoniae, despite the low susceptibility of the bacteria …

High-mobility group box 1 (HMGB1) concentration in serum or plasma has been proposed
as an important biological marker in various inflammation-related pathologies. We …

Introduction: Oxidative stress (OS) seems to be an important mediator of cellular injury, from
which sepsis can proceed. Studies have demonstrated the protective effect of controlled …

OBJECTIVE: To evaluate the efficacy of Shenfu decoction (SFD) prepared with a traditional
Chinese formula, on sepsis in rats with the condition induced by cecal ligation and puncture …

Background: Sepsis or infection is the second leading cause of death in people who are
intensive care units. Due to the side effects of NSAIDs drugs, the use of medicinal plants with …