CNS inflammation is a major driver of MS pathology. Differential immune responses,
including the adaptive and the innate immune system, are observed at various stages of MS …

Multiple sclerosis (MS) is an immune inflammatory disease, where the underlying etiological
cause remains elusive. Multiple triggering factors have been suggested, including …

Age is a critical risk factor for many neurologic conditions, including progressive multiple
sclerosis. Yet the mechanisms underlying the relationship are unknown. Using lysolecithin …

The most challenging aspect of secondary progressive multiple sclerosis (SPMS) is the lack
of efficient regenerative response for remyelination, which is carried out by the endogenous …

Background Although solid information on the natural history of primary progressive multiple
sclerosis (PPMS) is available, evidence regarding impact of disease activity on PPMS …

Background and Goals: Multiple sclerosis (MS) is a central nervous system inflammatory
disease where magnetic resonance imaging (MRI) is an important tool for diagnosis and …

Overview: We assessed the role of age and disease activity as new factors contributing to
establish the risk of progressive multifocal leucoencephalopathy in multiple sclerosis …

Introduction The aim of this study was to describe the real-word treatment and associated
healthcare resource use (HCRU) of multiple sclerosis (MS) patients, as stratified by different …

Background Studies on the predictors of progression for primary progressive multiple
sclerosis (PPMS) are limited and there is no information in the literature for populations …

Multiple sclerosis (MS) is a chronic, inflammatory, demyelinating and neurodegenerative
disease of the central nervous system. The majority (85–90%) of people with MS initially …