Evolving concepts on the role of dyslipidemia, bioenergetics, and inflammation in the pathogenesis and treatment of diabetic peripheral neuropathy

AM Stino, AE Rumora, B Kim… - Journal of the Peripheral …, 2020 - Wiley Online Library
Diabetic peripheral neuropathy (DPN) is one of the most widespread and disabling
neurological conditions, accounting for half of all neuropathy cases worldwide. Despite its …

[HTML][HTML] Protective effect of hydrogen sulfide on oxidative stress-induced neurodegenerative diseases

R Tabassum, NY Jeong, J Jung - Neural Regeneration Research, 2020 - journals.lww.com
Hydrogen sulfide is an antioxidant molecule that has a wide range of biological effects
against oxidative stress. Balanced oxidative stress is also vital for maintaining cellular …

Sensorimotor and pain‐related alterations of the gray matter and white matter in Type 2 diabetic patients with peripheral neuropathy

Y Zhang, M Qu, X Yi, P Zhuo, J Tang… - Human Brain …, 2020 - Wiley Online Library
Although diabetic peripheral neuropathy (DPN) has long been considered a disease of the
peripheral nervous system, recent neuroimaging studies have shown that alterations in the …

[HTML][HTML] Differential effects of empagliflozin on microvascular complications in murine models of type 1 and type 2 diabetes

SA Eid, PD O'Brien, LM Hinder, JM Hayes… - Biology, 2020 - mdpi.com
Simple Summary Type 1 and type 2 diabetes can lead to serious health problems that affect
many organs including the nerve, the eye, and the kidney. These health problems can be …

Progressive loss of corneal nerve fibers and sensitivity in rats modeling obesity and type 2 diabetes is reversible with omega-3 fatty acid intervention: supporting …

L Coppey, E Davidson, H Shevalye… - Diabetes, Metabolic …, 2020 - Taylor & Francis
Purpose To determine whether cornea nerve fiber density and/or corneal function are valid
markers for early detection and treatment of peripheral neuropathy in rats modeling …

Clinical and structural outcomes after rotator cuff repair in patients with diabetes: a meta-analysis

L Yang, J Zhang, D Ruan, K Zhao… - … Journal of Sports …, 2020 - journals.sagepub.com
Background: The impact of diabetes on clinical and structural outcomes after rotator cuff
repair remains controversial. Purpose/Hypothesis: The purpose of this study was to compare …

Activation of CaMKII and GluR1 by the PSD-95-GluN2B coupling-dependent phosphorylation of GluN2B in the spinal cord in a rat model of type-2 diabetic neuropathic …

YB Zhu, GL Jia, JW Wang, XY Ye, JH Lu… - … of Neuropathology & …, 2020 - academic.oup.com
The mechanisms underlying type-2 diabetic neuropathic pain (DNP) are unclear. This study
investigates the coupling of postsynaptic density-95 (PSD-95) to N-methyl-D-aspartate …

[HTML][HTML] The antioxidant, anti-apoptotic, and proliferative potency of argan oil against betamethasone-induced oxidative renal damage in rats

SH Orabi, TS Allam, SM Shawky, EAE Tahoun… - Biology, 2020 - mdpi.com
Simple Summary The present study aimed to investigate the protective effect of argan oil
against nephrotoxic effect following overdose and long-term administration of …

Long-chain acyl-CoA synthetase-1 mediates the palmitic acid-induced inflammatory response in human aortic endothelial cells

G Ren, S Bhatnagar, DJ Hahn… - American Journal of …, 2020 - journals.physiology.org
Saturated fatty acid (SFA) induces proinflammatory response through a Toll-like receptor
(TLR)-mediated mechanism, which is associated with cardiometabolic diseases such as …

Vibrotactile perception on the sole of the foot in an older group of people with normal glucose tolerance and type 2 diabetes

M Peterson, R Pingel, O Rolandsson… - SAGE Open …, 2020 - journals.sagepub.com
Objectives: To evaluate vibrotactile sense in an older group of people with normal glucose
tolerance and type 2 diabetes relative to other sensory tests. Methods: Vibration perception …