Recent update on basic mechanisms of spinal cord injury
Spinal cord injury (SCI) is a life-shattering neurological condition that affects between
250,000 and 500,000 individuals each year with an estimated two to three million people …
250,000 and 500,000 individuals each year with an estimated two to three million people …
Therapeutic repair for spinal cord injury: combinatory approaches to address a multifaceted problem
JM Griffin, F Bradke - EMBO molecular medicine, 2020 - embopress.org
The recent years saw the advent of promising preclinical strategies that combat the
devastating effects of a spinal cord injury (SCI) that are progressing towards clinical trials …
devastating effects of a spinal cord injury (SCI) that are progressing towards clinical trials …
The leading edge: Emerging neuroprotective and neuroregenerative cell-based therapies for spinal cord injury
CS Ahuja, A Mothe, M Khazaei… - Stem cells …, 2020 - academic.oup.com
Spinal cord injuries (SCIs) are associated with tremendous physical, social, and financial
costs for millions of individuals and families worldwide. Rapid delivery of specialized …
costs for millions of individuals and families worldwide. Rapid delivery of specialized …
The fate and function of oligodendrocyte progenitor cells after traumatic spinal cord injury
Oligodendrocyte progenitor cells (OPCs) are the most proliferative and dispersed population
of progenitor cells in the adult central nervous system, which allows these cells to rapidly …
of progenitor cells in the adult central nervous system, which allows these cells to rapidly …
Design of hydrogel-based scaffolds for the treatment of spinal cord injuries
N Ghane, MH Beigi, S Labbaf… - Journal of Materials …, 2020 - pubs.rsc.org
Spinal cord injury (SCI) is a traumatic lesion that diminishes sensory and/or motor neuronal
functionality, directly affecting the quality of the patient's life. Due to the central nervous …
functionality, directly affecting the quality of the patient's life. Due to the central nervous …
Schwann cell-like cells: origin and usability for repair and regeneration of the peripheral and central nervous system
A Hopf, DJ Schaefer, DF Kalbermatten, R Guzman… - Cells, 2020 - mdpi.com
Functional recovery after neurotmesis, a complete transection of the nerve fiber, is often poor
and requires a surgical procedure. Especially for longer gaps (> 3 mm), end-to-end suturing …
and requires a surgical procedure. Especially for longer gaps (> 3 mm), end-to-end suturing …
[HTML][HTML] Novel innovations in cell and gene therapies for spinal cord injury
Spinal cord injury (SCI) leads to chronic and multifaceted disability, which severely impacts
the physical and mental health as well as the socio-economic status of affected individuals …
the physical and mental health as well as the socio-economic status of affected individuals …
Behavioral testing in animal models of spinal cord injury
This review is based on a lecture presented at the Craig H. Neilsen Foundation sponsored
Spinal Cord Injury Training Program at Ohio State University. We discuss the advantages …
Spinal Cord Injury Training Program at Ohio State University. We discuss the advantages …
Regenerative medicine for spinal cord injury: focus on stem cells and biomaterials
S Papa, F Pizzetti, G Perale… - Expert opinion on …, 2020 - Taylor & Francis
Introduction Spinal cord injury (SCI) is a dramatic medical pathology consequence of a
trauma (primary injury). However, most of the post-traumatic degeneration of the tissue is …
trauma (primary injury). However, most of the post-traumatic degeneration of the tissue is …
[HTML][HTML] Transplantation of skin precursor-derived schwann cells yields better locomotor outcomes and reduces bladder pathology in rats with chronic spinal cord …
Cell transplantation for spinal cord injury (SCI) has largely been studied in sub-acute
settings within 1–2 weeks of injury. In contrast, here we transplanted skin-derived precursors …
settings within 1–2 weeks of injury. In contrast, here we transplanted skin-derived precursors …