Exosomes: from potential culprits to new therapeutic promise in the setting of cardiac fibrosis
R Tikhomirov, B Reilly-O'Donnell, F Catapano… - Cells, 2020 - mdpi.com
Fibrosis is a significant global health problem associated with many inflammatory and
degenerative diseases affecting multiple organs, individually or simultaneously. Fibrosis …
degenerative diseases affecting multiple organs, individually or simultaneously. Fibrosis …
miR-26b inhibits isoproterenol-induced cardiac fibrosis via the Keap1/Nrf2 signaling pathway
S Xian, J Li, Z Zhang - Experimental and Therapeutic …, 2020 - spandidos-publications.com
A critical event in cardiac fibrosis is the transformation of cardiac fibroblasts (CFs) into
myofibroblasts. MicroRNAs (miRNAs) have been reported to be critical regulators in the …
myofibroblasts. MicroRNAs (miRNAs) have been reported to be critical regulators in the …
The left ventricle undergoes biomechanical and gene expression changes in response to increased right ventricular pressure overload
VO Kheyfets, MJ Dufva, M Boehm, X Tian… - Physiological …, 2020 - Wiley Online Library
Pulmonary hypertension (PH) results in right ventricular (RV) pressure overload and
eventual failure. Current research efforts have focused on the RV while overlooking the left …
eventual failure. Current research efforts have focused on the RV while overlooking the left …