During the past decade, mass spectrometry imaging (MSI) has become a robust and
versatile methodology to support modern pharmaceutical research and development. The …

Ambient mass spectrometry imaging (AMSI) is a molecular imaging technique developed in
recent years for in situ and real time visualization of the distribution of chemical compounds …

A new tissue sample embedding and processing method is presented that provides
downstream compatibility with numerous different histological, molecular biology, and …

Mass spectrometry imaging (MSI) provides information on the spatial distribution of
molecules within a biological substrate without the requirement for labeling. Its broad …

ABSTRACT Introduction: Three-dimensional (3D) cell cultures have become increasingly
important materials to investigate biological processes and drug efficacy and toxicity. The …

Background: For the treatment of respiratory disease, inhaled drug delivery aims to provide
direct access to pharmacological target sites while minimizing systemic exposure. Despite …

This thesis investigates the possibility of using ion beam analysis (IBA) with mass
spectrometry imaging (MSI) techniques for multimodal elemental and molecular imaging on …

Mass spectrometry has recently become a popular approach for the determination of the
spatial distribution of drugs in vivo and in vitro, which has given rise to the field of mass …

This thesis described the synthesis, carachterization, and application of bioconjugated metal-
based compounds. The bioconjugated Pd-based metallocages are non-toxic to healthy …