The α2 adrenergic receptors (α2ARs) are G protein-coupled receptors (GPCRs) that
respond to adrenaline and noradrenaline and couple to the Gi/o family of G proteins. α2ARs …

Zerumbone, a monocyclic sesquiterpene from the wild ginger plant Zingiber zerumbet (L.)
Smith, attenuates allodynia and hyperalgesia. Currently, its mechanisms of action in …

Noise anxiety in horses caused by fireworks has not been studied before, even though it is a
well-known problem by owners. Stressed horses risk injuring themselves and handlers and …

A dexmedetomidina é um alfa2-agonista seletivo, que promove analgesia, relaxamento
muscular, hipnose, aumento de pressão arterial e vasoconstrição periférica, podendo …

Pain management of the laminitic horse can be extremely challenging. Given the various
types of pain these horses experience, a multimodal approach to pain management of the …