Cognitive impact of COVID-19: looking beyond the short term

S Miners, PG Kehoe, S Love - Alzheimer's research & therapy, 2020 - Springer
COVID-19 is primarily a respiratory disease but up to two thirds of hospitalised patients show
evidence of central nervous system (CNS) damage, predominantly ischaemic, in some …

Pharmacology and perspectives in erectile dysfunction in man

E Mitidieri, G Cirino, RE di Villa Bianca… - Pharmacology & …, 2020 - Elsevier
Penile erection is a perfect example of microcirculation modulated by psychological factors
and hormonal status. It is the result of a complex neurovascular process that involves the …

COVID‐19 and hypertension—evidence and practical management: guidance from the HOPE Asia network

K Kario, Y Morisawa, A Sukonthasarn… - The Journal of …, 2020 - Wiley Online Library
There are several risk factors for worse outcomes in patients with coronavirus 2019 disease
(COVID‐19). Patients with hypertension appear to have a poor prognosis, but there is no …

Emerging mechanisms of pulmonary vasoconstriction in SARS-CoV-2-induced acute respiratory distress syndrome (ARDS) and potential therapeutic targets

H Karmouty-Quintana, RA Thandavarayan… - International journal of …, 2020 - mdpi.com
The 1918 influenza killed approximately 50 million people in a few short years, and now, the
world is facing another pandemic. In December 2019, a novel coronavirus named severe …

The vasoactive Mas receptor in essential hypertension

AL Povlsen, D Grimm, M Wehland, M Infanger… - Journal of Clinical …, 2020 - mdpi.com
The renin–angiotensin–aldosterone system (RAAS) has been studied extensively, and with
the inclusion of novel components, it has become evident that the system is much more …

[HTML][HTML] Urgent need for evaluating agonists of angiotensin-(1-7)/Mas receptor axis for treating patients with COVID-19

A Shete - International Journal of Infectious Diseases, 2020 - Elsevier
ACE2 is a receptor of entry of SARS-CoV-2 into the host cells, and its upregulation has been
implicated in increasing susceptibility of individuals to this infection. The clinical picture of …

Updates on gene therapy for diabetic retinopathy

JH Wang, GE Roberts, GS Liu - Current Diabetes Reports, 2020 - Springer
Abstract Purpose of Review Diabetic retinopathy (DR), a leading cause of visual impairment
in the developed country, is characterized by vascular lesions and neuronal damage of the …

Local ocular renin–angiotensin–aldosterone system: Any connection with intraocular pressure? A comprehensive review

M Holappa, H Vapaatalo, A Vaajanen - Annals of Medicine, 2020 - Taylor & Francis
The renin–angiotensin system (RAS) is one of the oldest and most extensively studied
human peptide cascades, well-known for its role in regulating blood pressure. When …

Significance of the renin-angiotensin system in clinical conditions

V Đambić, Đ Pojatić, A Stažić… - Selected Chapters from the …, 2020 - books.google.com
The renin-angiotensin system, in both its circulating and local tissue roles, is intertwined with
multiple other regulatory and signalling mechanisms in various tissues and organ systems. It …

The serum angiotensin-converting enzyme 2 and angiotensin-(1-7) concentrations after optimal therapy for acute decompensated heart failure with reduced ejection …

S Hisatake, S Kiuchi, T Kabuki, T Oka… - Bioscience …, 2020 - portlandpress.com
Objective: Elucidation of the role of angiotensin-converting enzyme (ACE) 2
(ACE2)/angiotensin (Ang)-(1-7)/Mas receptor axis in heart failure is necessary. No previous …