Long noncoding RNAs in cancer: from discovery to therapeutic targets
R Choudhari, MJ Sedano, AL Harrison… - Advances in clinical …, 2020 - Elsevier
Long noncoding RNAs (lncRNAs) have recently gained considerable attention as key
players in biological regulation; however, the mechanisms by which lncRNAs govern …
players in biological regulation; however, the mechanisms by which lncRNAs govern …
[HTML][HTML] Exosomal long non-coding RNAs in lung diseases
Within the non-coding genome landscape, long non-coding RNAs (lncRNAs) and their
secretion within exosomes are a window that could further explain the regulation, the …
secretion within exosomes are a window that could further explain the regulation, the …
[HTML][HTML] Exosome-transmitted lncRNA UFC1 promotes non-small-cell lung cancer progression by EZH2-mediated epigenetic silencing of PTEN expression
X Zang, J Gu, J Zhang, H Shi, S Hou, X Xu… - Cell death & …, 2020 - nature.com
Abstract Long non-coding RNAs (LncRNAs) have been suggested as important regulators of
cancer development and progression in non-small cell lung cancer (NSCLC). Nevertheless …
cancer development and progression in non-small cell lung cancer (NSCLC). Nevertheless …
[HTML][HTML] The Tug1 lncRNA locus is essential for male fertility
Abstract Background Several long noncoding RNAs (lncRNAs) have been shown to function
as components of molecular machines that play fundamental roles in biology. While the …
as components of molecular machines that play fundamental roles in biology. While the …
LncRNA TUG1 mediates ischemic myocardial injury by targeting miR-132-3p/HDAC3 axis
Q Su, Y Liu, XW Lv, RX Dai… - American Journal of …, 2020 - journals.physiology.org
Increased production of reactive oxygen species (ROS) significantly contributed to the
pathogenesis of acute myocardial infarction (AMI). Recent studies suggest that hypoxia …
pathogenesis of acute myocardial infarction (AMI). Recent studies suggest that hypoxia …
Pathophysiological functions of the lncRNA TUG1
C Guo, Y Qi, J Qu, L Gai, Y Shi… - Current pharmaceutical …, 2020 - ingentaconnect.com
Background: Long non-coding RNAs (lncRNAs) with little or no coding capacity are
associated with a plethora of cellular functions, participating in various biological processes …
associated with a plethora of cellular functions, participating in various biological processes …
Long non-coding RNA in lung cancer
Z Chen, T Lei, X Chen, J Gu, J Huang, B Lu, Z Wang - Clinica chimica acta, 2020 - Elsevier
Lung cancer is the leading cause of cancer-related death worldwide. Owing to the difficulty
in early diagnosis and the lack of effective treatment strategies, the 5-year survival rates for …
in early diagnosis and the lack of effective treatment strategies, the 5-year survival rates for …
[HTML][HTML] New insights into long non-coding RNAs in non-small cell lung cancer
R Ye, R Tang, S Gan, R Li, Y Cheng, L Guo… - Biomedicine & …, 2020 - Elsevier
Lung cancer is a malignant tumor that seriously threatens human life and health. Non-small
cell lung cancer (NSCLC) accounts for 85% of all lung cancer cases, and its global 5-year …
cell lung cancer (NSCLC) accounts for 85% of all lung cancer cases, and its global 5-year …
[HTML][HTML] Role of taurine, its haloamines and its lncRNA TUG1 in both inflammation and cancer progression. On the road to therapeutics?
S Baliou, AM Kyriakopoulos… - International …, 2020 - spandidos-publications.com
For one century, taurine is considered as an end product of sulfur metabolism. In this review,
we discuss the beneficial effect of taurine, its haloamines and taurine upregulated gene 1 …
we discuss the beneficial effect of taurine, its haloamines and taurine upregulated gene 1 …
[HTML][HTML] Deciphering the mounting complexity of the p53 regulatory network in correlation to long non-coding RNAs (lncRNAs) in ovarian cancer
Amongst the various gynecological malignancies affecting female health globally, ovarian
cancer is one of the predominant and lethal among all. The identification and functional …
cancer is one of the predominant and lethal among all. The identification and functional …