Highlights•Stable isotopes do not have a significant impact on the production of specialized
metabolites in organisms, including plants.•Mass spectrometry-based metabolomics using …

Monoterpene indole alkaloids (MIAs) in medicinal plants remain uncharacterized owing to
their complicated structure by metabolomics using liquid chromatography–tandem mass …

Alzheimer's disease (AD) is a chronic and progressive neurodegenerative disorder.
Rhodiola crenulata extract (RCE) has shown its protective effects on AD, however, the …

Profiling impurities for the active pharmaceutical ingredients (APIs) is an indispensable step
in drug development process. Nowadays, high resolution mass spectrometry is the first …

Rationale In the process of the identification of unknown metabolites, the most important
thing is to determine their real chemical formulae according to the accurate masses which …

Fungi of the genus Alternaria are widely occurring plant pathogens infecting a multitude of
crops, fruits, and vegetables. In the present thesis, a sensitive LC-MS/MS method for the …

Rationale Recently, isotopic fine structures derived from Fourier transform ion cyclotron
resonance mass spectrometry have been used to determine the molecular formula for …

The molybdenum (Mo)-catalyzed oxidation of sulfide under neutral conditions yields sulfone.
This reaction proceeds more smoothly than olefin epoxidation and primary or secondary …

Imaging mass spectrometry (IMS) is an analytical method for visualizing the localization of
metabolites. IMS analysis involves performing spatial mass spectrometry in coordinates …