Biomarkers for Alzheimer's disease early diagnosis

E Ausó, V Gómez-Vicente, G Esquiva - Journal of Personalized Medicine, 2020 - mdpi.com
Alzheimer's disease (AD) is the most common cause of dementia, affecting the central
nervous system (CNS) through the accumulation of intraneuronal neurofibrillary tau tangles …

Structural magnetic resonance imaging for the early diagnosis of dementia due to Alzheimer's disease in people with mild cognitive impairment

G Lombardi, G Crescioli, E Cavedo… - Cochrane Database …, 2020 - cochranelibrary.com
Background Mild cognitive impairment (MCI) due to Alzheimer's disease is the symptomatic
predementia phase of Alzheimer's disease dementia, characterised by cognitive and …

Retinal microvasculature dysfunction is associated with Alzheimer's disease and mild cognitive impairment

J Chua, Q Hu, M Ke, B Tan, J Hong, X Yao… - Alzheimer's Research & …, 2020 - Springer
Abstracts Background The retina and brain share many neuronal and vasculature
characteristics. We investigated the retinal microvasculature in Alzheimer's disease (AD) …

Functional magnetic resonance imaging of the trail-making test in older adults

N Talwar, NW Churchill, MA Hird, F Tam, SJ Graham… - PLoS …, 2020 - journals.plos.org
The trail-making test (TMT) is a popular neuropsychological test, which is used extensively
to measure cognitive impairment associated with neurodegenerative disorders in older …

Predicting the progression of mild cognitive impairment to Alzheimer's disease by longitudinal magnetic resonance imaging-based dictionary learning

Y Lin, K Huang, H Xu, Z Qiao, S Cai, Y Wang… - Clinical …, 2020 - Elsevier
Objective Efficient prediction of the progression of mild cognitive impairment (MCI) to
Alzheimer's disease (AD) is important for the early intervention and management of AD. The …

Associations of rest-activity patterns with amyloid burden, medial temporal lobe atrophy, and cognitive impairment

HW Roh, J Choi, NR Kim, YS Choe, JW Choi… - …, 2020 - thelancet.com
Background We sought to investigate the possible associations of rest-activity patterns with
cortical amyloid burden, medial temporal lobe (MTL) neurodegeneration, and cognitive …

The entorhinal cortex atrophy score is diagnostic and prognostic in mild cognitive impairment

A Traschütz, SJ Enkirch, N Polomac… - Journal of …, 2020 - content.iospress.com
Background: Structural magnetic resonance imaging (MRI) is routinely performed in patients
with mild cognitive impairment (MCI), but diagnostic accuracy to detect early cerebral …

Combining visual rating scales for medial temporal lobe atrophy and posterior atrophy to identify amnestic mild cognitive impairment from cognitively normal older …

C Sheng, Y Sun, M Wang, X Wang… - Journal of …, 2020 - content.iospress.com
Background: Visual rating scales for medial temporal lobe atrophy (MTA) and posterior
atrophy (PA) have been reported to be useful for Alzheimer's disease diagnosis in routine …

Pragmatic realities on brain imaging techniques and image fusion for Alzheimer's disease

PSJ Kumar, Y Yung, M Pan - International Journal of …, 2020 - inderscienceonline.com
Alzheimer's disease is the absolute generous of age-related neurodegenerative syndrome.
It specifies substantial brain atrophy, amnesia and major neuro-logic disintegration. Brain …

[HTML][HTML] Mild cognitive impairment: Prognosis and treatment

R Petersen, A Orenstein - UpToDate, 2020 - medilib.ir
INTRODUCTION—Mild cognitive impairment (MCI) is an intermediate clinical state between
normal cognition and dementia. While specific subtle changes in cognition are frequently …