[HTML][HTML] Biocompatibility of biomaterials for nanoencapsulation: Current approaches

BA Witika, PA Makoni, SK Matafwali, B Chabalenge… - Nanomaterials, 2020 - mdpi.com
Nanoencapsulation is an approach to circumvent shortcomings such as reduced
bioavailability, undesirable side effects, frequent dosing and unpleasant organoleptic …

[PDF][PDF] Recent advances in nonlinear optics for bio-imaging applications

S Zhang, L Liu, S Ren, Z Li, Y Zhao, Z Yang… - Opto-Electronic …, 2020 - researching.cn
Nonlinear optics, which is a subject for studying the interaction between intense light and
materials, has great impact on various research fields. Since many structures in biological …

Organic Spherical Nucleic Acids for the Transport of a NIR‐II‐Emitting Dye Across the Blood–Brain Barrier

F Xiao, L Lin, Z Chao, C Shao, Z Chen… - Angewandte Chemie …, 2020 - Wiley Online Library
DNA nanotechnology plays an increasingly important role in the biomedical field; however,
its application in the design of organic nanomaterials is underexplored. Herein, we report …

Specific targeting of ovarian tumor-associated macrophages by large, anionic nanoparticles

T Haber, YR Cornejo, S Aramburo… - Proceedings of the …, 2020 - National Acad Sciences
Immunotherapy is emerging as one of the most effective methods for treating many cancers.
However, immunotherapy can still introduce significant off-target toxicity, and methods are …

[HTML][HTML] Microfluidic-assisted preparation of RGD-decorated nanoparticles: exploring integrin-facilitated uptake in cancer cell lines

JM Rios De La Rosa, A Spadea, R Donno, E Lallana… - Scientific Reports, 2020 - nature.com
This study is about fine tuning the targeting capacity of peptide-decorated nanoparticles to
discriminate between cells that express different integrin make-ups. Using microfluidic …

Poly(lactic-co-glycolic) Acid–Lipid Hybrid Microparticles Enhance the Intracellular Uptake and Antibacterial Activity of Rifampicin

S Maghrebi, P Joyce, M Jambhrunkar… - … applied materials & …, 2020 - ACS Publications
An urgent demand exists for the development of effective carrier systems that systematically
enhance the cellular uptake and localization of antibiotic drugs for the treatment of …

Next generation miRNA inhibition using short anti-seed PNAs encapsulated in PLGA nanoparticles

S Malik, J Lim, FJ Slack, DT Braddock… - Journal of Controlled …, 2020 - Elsevier
Selective inhibition of microRNAs (miRNAs) offers a new avenue for cancer therapeutics.
While most of the current anti-miRNA (antimiR) reagents target full length miRNAs, here we …

[HTML][HTML] Intravenously Administered, Retinoid Activating Nanoparticles Increase Lifespan and Reduce Neurodegeneration in the SOD1G93A Mouse Model of ALS

DX Medina, EP Chung, CD Teague… - … in bioengineering and …, 2020 - frontiersin.org
Dysregulation of the retinoic acid (RA) signaling pathway is observed in amyotrophic lateral
sclerosis (ALS) and other neurodegenerative disorders. Here, we investigated the …

Engineering PLGA–lipid hybrid microparticles for enhanced macrophage uptake

S Maghrebi, M Jambhrunkar, P Joyce… - ACS Applied Bio …, 2020 - ACS Publications
Strategies to improve the uptake of particulate delivery systems to macrophages are
required for the advancement of therapeutic solutions to a range of disease states, including …

Nanohybrid biodegradable scaffolds for TGF-β3 release for the chondrogenic differentiation of human mesenchymal stem cells

M Qasim, NXT Le, TPT Nguyen, DS Chae… - International Journal of …, 2020 - Elsevier
An ideal scaffold for bone tissue engineering should have chondroinductive, biodegradable,
and biocompatible properties, as well as the ability to absorb and slowly release the …