Targeting connexin 43 provides anti-inflammatory effects after intracerebral hemorrhage injury by regulating YAP signaling
H Yu, X Cao, W Li, P Liu, Y Zhao, L Song… - Journal of …, 2020 - Springer
Background In the central nervous system (CNS), connexin 43 (Cx43) is mainly expressed
in astrocytes and regulates astrocytic network homeostasis. Similar to Cx43 overexpression …
in astrocytes and regulates astrocytic network homeostasis. Similar to Cx43 overexpression …
Connexin 43 deletion in astrocytes promotes CNS remyelination by modulating local inflammation
T Li, J Niu, G Yu, P Ezan, C Yi, X Wang, A Koulakoff… - Glia, 2020 - Wiley Online Library
As the most abundant gap junction protein in the central nervous system (CNS), astrocytic
connexin 43 (Cx43) maintains astrocyte network homeostasis, affects oligodendroglial …
connexin 43 (Cx43) maintains astrocyte network homeostasis, affects oligodendroglial …
[HTML][HTML] Mechanosensitive collaboration between integrins and connexins allows nutrient and antioxidant transport into the lens
J Liu, MA Riquelme, Z Li, Y Li, Y Tong… - The Journal of Cell …, 2020 - ncbi.nlm.nih.gov
The delivery of glucose and antioxidants is vital to maintain homeostasis and lens
transparency. Here, we report a new mechanism whereby mechanically activated connexin …
transparency. Here, we report a new mechanism whereby mechanically activated connexin …
[HTML][HTML] Interferon-γ and high glucose-induced opening of Cx43 hemichannels causes endothelial cell dysfunction and damage
JC Sáez, S Contreras-Duarte, VC Labra… - … et Biophysica Acta (BBA …, 2020 - Elsevier
Both IFN-γ or high glucose have been linked to systemic inflammatory imbalance with
serious repercussions not only for endothelial function but also for the formation of the …
serious repercussions not only for endothelial function but also for the formation of the …
Connexins in oligodendrocytes and astrocytes: Possible factors for demyelination in multiple sclerosis
CY Xia, JK Xu, CH Pan, WW Lian, Y Yan, BZ Ma… - Neurochemistry …, 2020 - Elsevier
Increasing evidences support that glial connexins are involved in the demyelination
pathology of multiple sclerosis (MS), a chronic inflammatory demyelinating disorder. Here …
pathology of multiple sclerosis (MS), a chronic inflammatory demyelinating disorder. Here …
Connexins in neuromyelitis optica: a link between astrocytopathy and demyelination
C Richard, A Ruiz, S Cavagna, M Bigotte, S Vukusic… - Brain, 2020 - academic.oup.com
Neuromyelitis optica, a rare neuroinflammatory demyelinating disease of the CNS, is
characterized by the presence of specific pathogenic autoantibodies directed against the …
characterized by the presence of specific pathogenic autoantibodies directed against the …