No easy way out for EZH2: its pleiotropic, noncanonical effects on gene regulation and cellular function
Enhancer of zeste homolog 2 (EZH2) plays critical roles in a range of biological processes
including organ development and homeostasis, epigenomic and transcriptomic regulation …
including organ development and homeostasis, epigenomic and transcriptomic regulation …
EZH2 function in immune cell development
The polycomb repressive complex 2 (PRC2) consists of three core components EZH2,
SUZ12 and EED. EZH2 catalyzes the methylation of lysine 27 of histone H3, a modification …
SUZ12 and EED. EZH2 catalyzes the methylation of lysine 27 of histone H3, a modification …
Histone Lysine Methylation Dynamics Control EGFR DNA Copy-Number Amplification
Acquired chromosomal DNA copy gains are a feature of many tumors; however, the
mechanisms that underpin oncogene amplification are poorly understood. Recent studies …
mechanisms that underpin oncogene amplification are poorly understood. Recent studies …
Long noncoding RNA PART1 restrains aggressive gastric cancer through the epigenetic silencing of PDGFB via the PLZF-mediated recruitment of EZH2
H Han, S Wang, J Meng, G Lyu, G Ding, Y Hu, L Wang… - Oncogene, 2020 - nature.com
Current reports refer to the role of long noncoding RNA (lncRNA) prostate androgen-
regulated transcript 1 (PART1) as a tumor suppressor in some types of cancer but as an …
regulated transcript 1 (PART1) as a tumor suppressor in some types of cancer but as an …
Analysis of expression of candidate genes for polycystic ovary syndrome in adult and fetal human and fetal bovine ovaries
M Liu, K Hummitzsch, MD Hartanti… - Biology of …, 2020 - academic.oup.com
Polycystic ovary syndrome (PCOS) appears to have a genetic predisposition and a fetal
origin. We compared the expression levels of 25 PCOS candidate genes from adult control …
origin. We compared the expression levels of 25 PCOS candidate genes from adult control …
[PDF][PDF] 应用肿瘤数据库信息я 析ZBTB16 在肝癌中的表达及其功能初步研究
于玲， 于敏 - 现代免疫学, 2020 - shmy.shsmu.edu.cn
ZincfingerandBTBdomaincontaining16 (ZBTB16), 亦称早幼粒细胞白血病锌指蛋白(
promyelocyticleukemiazinc finger, PLZF), 作为种转录抑制因子在调控细胞周期, 增殖 …
promyelocyticleukemiazinc finger, PLZF), 作为种转录抑制因子在调控细胞周期, 增殖 …
Genome-wide DNA-binding profile of SRY-box transcription factor 3 (SOX3) in mouse testes
D McAninch, EP Thomson… - Reproduction, Fertility and …, 2020 - CSIRO Publishing
Spermatogenesis is the male version of gametogenesis, where germ cells are transformed
into haploid spermatozoa through a tightly controlled series of mitosis, meiosis and …
into haploid spermatozoa through a tightly controlled series of mitosis, meiosis and …