Recovery of renal function following kidney-specific VEGF therapy in experimental renovascular disease

JE Engel, ML Williams, E Williams, C Azar… - American journal of …, 2020 - karger.com
Background: Chronic renovascular disease (RVD) can lead to a progressive loss of renal
function, and current treatments are inefficient. We designed a fusion of vascular endothelial …

Molecular targeting of renal inflammation using drug delivery technology to inhibit NF-κB improves renal recovery in chronic kidney disease

AR Chade, ML Williams, JE Engel… - American Journal …, 2020 - journals.physiology.org
Inflammation is a major determinant for the progression of chronic kidney disease (CKD). NF-
κB is a master transcription factor upregulated in CKD that promotes inflammation and …

A Boolean model of microvascular rarefaction to predict treatment outcomes in renal disease

E Williams, AR Chade - Scientific Reports, 2020 - nature.com
Despite advances in renovascular disease (RVD) research, gaps remain between
experimental and clinical outcomes, translation of results, and the understanding of …

[HTML][HTML] Translational Physiology: Molecular targeting of renal inflammation using drug delivery technology to inhibit NF-κB improves renal recovery in chronic kidney …

AR Chade, ML Williams, JE Engel… - American Journal of …, 2020 - ncbi.nlm.nih.gov
Inflammation is a major determinant for the progression of chronic kidney disease (CKD). NF-
κB is a master transcription factor upregulated in CKD that promotes inflammation and …