Arabidopsis REM16 acts as a B3 domain transcription factor to promote flowering time via directly binding to the promoters of SOC1 and FT

Y Yu, L Qiao, J Chen, Y Rong, Y Zhao, X Cui… - The Plant …, 2020 - Wiley Online Library
Actin depolymerizing factor (ADF) is a key modulator for dynamic organization of actin
cytoskeleton. Interestingly, it was found that the ADF1 gene silencing delays flowering, but …

Keratin 17 regulates nuclear morphology and chromatin organization

JT Jacob, RR Nair, BG Poll, CM Pineda… - Journal of cell …, 2020 - journals.biologists.com
ABSTRACT Keratin 17 (KRT17; K17), a non-lamin intermediate filament protein, was
recently found to occur in the nucleus. We report here on K17-dependent differences in …

β-actin contributes to open chromatin for activation of the adipogenic pioneer factor CEBPA during transcriptional reprograming

MA Al-Sayegh, SR Mahmood, SBA Khair… - Molecular biology of …, 2020 - Am Soc Cell Biol
Adipogenesis is regulated by a cascade of signals that drive transcriptional reprogramming
in adipocytes. Here, we report that nuclear actin regulates the chromatin states that establish …

Nuclear myosin 1 activates p21 gene transcription in response to DNA damage through a chromatin-based mechanism

T Venit, K Semesta, S Farrukh, M Endara-Coll… - Communications …, 2020 - nature.com
Abstract Nuclear myosin 1 (NM1) has been implicated in key nuclear functions. Together
with actin, it has been shown to initiate and regulate transcription, it is part of the chromatin …

Silicon-incorporated nanohydroxyapatite-reinforced poly (ε-caprolactone) film to enhance osteogenesis for bone tissue engineering applications

T Lei, W Zhang, H Qian, PN Lim, E San Thian… - Colloids and Surfaces B …, 2020 - Elsevier
Biomaterials composed of polymers and bioceramics have great prospects to repair large
and complicated bone defects. Here, we developed a composite film consisting of poly (ε …

Nuclear actin and myosin in chromatin regulation and maintenance of genome integrity

T Venit, SR Mahmood, M Endara-Coll… - International Review of …, 2020 - Elsevier
Cytoskeletal proteins are beginning to be considered as key regulators of nuclear function.
Among them, actin and myosin have been implicated in numerous tasks, including …

EZH2 reduction is an essential mechanoresponse for the maintenance of super-enhancer polarization against compressive stress in human periodontal ligament stem …

Q Li, X Sun, Y Tang, Y Qu, Y Zhou, Y Zhang - Cell death & disease, 2020 - nature.com
Despite the ubiquitous mechanical cues at both spatial and temporal dimensions, cell
identities and functions are largely immune to the everchanging mechanical stimuli. To …

Time for rethinking the different β‐actin transgenic mouse models?

B Vanslembrouck, C Ampe, J van Hengel - Cytoskeleton, 2020 - Wiley Online Library
The actin family is crucial for many cellular processes and in mammals muscle and non‐
muscle forms exist. The latter group contains cytoplasmic‐β‐actin and cytoplasmic‐γ‐actin …

[PDF][PDF] Exploring the three-dimensional organization of the murine intercalated disc and unraveling the connection between the intercalated disc and the cytoskeleton …

B Vanslembrouck - 2020 - biblio.ugent.be
The heart muscle is responsible for pumping around 280 liters of blood per hour around the
human body. It mainly consists of cardiac myocytes that are organized in repeating …

[PDF][PDF] JB Review A dynamic actin-dependent nucleoskeleton and cell identity

T Venit, NH El Said, SR Mahmood, P Percipalle - researchgate.net
Actin is an essential regulator of cellular functions. In the eukaryotic cell nucleus, actin
regulates chromatin as a bona fide component of chromatin remodelling complexes, it …