The human gastrointestinal (gut) microbiota comprises diverse and dynamic populations of
bacteria, archaea, viruses, fungi, and protozoa, coexisting in a mutualistic relationship with …

The role of IL-22 in intestinal health and disease | Journal of Experimental Medicine |
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The intestinal mucosa serves both as a conduit for the uptake of food-derived nutrients and
microbiome-derived metabolites, and as a barrier that prevents tissue invasion by …

The gut is an efficient barrier which protects against the passage of pathogenic
microorganisms and potential harmful macromolecules into the body, in addition to its …

The multifaceted organization of the immune system involves not only patrolling
lymphocytes that constantly monitor antigen-presenting cells in secondary lymphoid organs …

Studies in recent years have uncovered the crucial function of neuroimmune interactions in
maintaining tissue homeostasis and protection. Immune and neuronal cells are often …

Group 3 innate lymphoid cell (ILC3)-mediated production of the cytokine interleukin-22 (IL-
22) is critical for the maintenance of immune homeostasis in the gastrointestinal tract. Here …

Innate lymphoid cells (ILCs) reside in mucosal surfaces to potentiate immune responses,
sustain mucosal integrity and maintain tissue homeostasis. However, how tumor infiltrating …

Emerging evidence implicates gut microbiota have an important role in ulcerative colitis
(UC). Previous study indicated that Evodiamine (EVO) can alleviate colitis through …

Group 3 innate lymphoid cells (ILC3s) have emerged as master regulators of intestinal
health and tissue homeostasis in mammals. Through a diverse array of cytokines and …