Alterations in tumour metabolism and acid/base regulation result in the formation of a hostile
environment, which fosters tumour growth and metastasis. Acid/base homoeostasis in …

Photodynamic therapy (PDT), as a robust strategy, has long been applied to cancer
treatment owing to the meaningful breakthroughs and unique advantages, including …

The extracellular adenosine triphosphate (ATP) concentration is highly elevated in the tumor
microenvironment (TME) and remains tightly regulated in normal tissues. Using phage …

The purpose of this study was to construct and characterize iron oxide nanoparticles
(IONPCO) for intracellular delivery of the anthracycline doxorubicin (DOX; IONPDOX) in …

Synthetic molecular communication (MC) is a new communication engineering paradigm
which is expected to enable revolutionary applications such as smart drug delivery and real …

To avoid toxicity of multifunctional nanomaterials in bioapplication, the biodegradable
inorganic nanoparticles (NPs) must be our main focus. In the work, we firstly developed …

D-α-tocopherol polyethylene glycol 1000 succinate (TPGS) is a pharmaceutical excipient
approved by Chinese NMPA and FDA of USA. It's widely applied as a multifunctional drug …

Solid tumors are metabolically highly active tissues, which produce large amounts of acid.
The acid/base balance in tumor cells is regulated by the concerted interplay between a …

Favorable blood flow within solid tumors has become the principal strategy for drug delivery.
The use of thrombolytic drugs, such as tissue plasminogen activator (t-PA), in combination …

While liposomes have proven to be effective drug delivery nanocarriers, their therapeutic
attributes could be improved through the development of clinically viable triggered release …