Cognitive impact of COVID-19: looking beyond the short term
COVID-19 is primarily a respiratory disease but up to two thirds of hospitalised patients show
evidence of central nervous system (CNS) damage, predominantly ischaemic, in some …
evidence of central nervous system (CNS) damage, predominantly ischaemic, in some …
Cerebral amyloid angiopathy and Alzheimer disease—one peptide, two pathways
SM Greenberg, BJ Bacskai… - Nature Reviews …, 2020 - nature.com
The shared role of amyloid-β (Aβ) deposition in cerebral amyloid angiopathy (CAA) and
Alzheimer disease (AD) is arguably the clearest instance of crosstalk between …
Alzheimer disease (AD) is arguably the clearest instance of crosstalk between …
Early postmortem brain MRI findings in COVID-19 non-survivors
T Coolen, V Lolli, N Sadeghi, A Rovai, N Trotta… - Neurology, 2020 - AAN Enterprises
Objectives The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is
considered to have potential neuroinvasiveness that might lead to acute brain disorders or …
considered to have potential neuroinvasiveness that might lead to acute brain disorders or …
From stroke to dementia: a comprehensive review exposing tight interactions between stroke and amyloid-β formation
R Goulay, L Mena Romo, EM Hol… - Translational Stroke …, 2020 - Springer
Stroke and Alzheimer's disease (AD) are cerebral pathologies with high socioeconomic
impact that can occur together and mutually interact. Vascular factors predisposing to …
impact that can occur together and mutually interact. Vascular factors predisposing to …
[HTML][HTML] Clinical relevance of cerebral small vessel diseases
M Pasi, C Cordonnier - Stroke, 2020 - journals.lww.com
Until recent years, cerebral small vessel disease (SVD) has drawn little attention mostly
because small cerebral arteries were difficult to observe in imaging and in vivo studies …
because small cerebral arteries were difficult to observe in imaging and in vivo studies …
Perivascular unit: This must be the place. The anatomical crossroad between the immune, vascular and nervous system
F Troili, V Cipollini, M Moci, E Morena… - Frontiers in …, 2020 - frontiersin.org
Most neurological disorders seemingly have heterogenous pathogenesis, with overlapping
contribution of neuronal, immune and vascular mechanisms of brain injury. The perivascular …
contribution of neuronal, immune and vascular mechanisms of brain injury. The perivascular …
Alzheimer‐related cerebrovascular disease in Down syndrome
Objective Adults with Down syndrome (DS) develop Alzheimer disease (AD) pathology by
their 5th decade. Compared with the general population, traditional vascular risks in adults …
their 5th decade. Compared with the general population, traditional vascular risks in adults …
Neuropathologic and cognitive correlates of enlarged perivascular spaces in a community-based cohort of older adults
C Javierre-Petit, JA Schneider, A Kapasi, N Makkinejad… - Stroke, 2020 - Am Heart Assoc
Background and Purpose: Enlarged perivascular spaces (EPVS) have been associated with
aging, increased stroke risk, decreased cognitive function, and vascular dementia. However …
aging, increased stroke risk, decreased cognitive function, and vascular dementia. However …
Association of enlarged perivascular spaces and anticoagulant-related intracranial hemorrhage
JG Best, C Barbato, G Ambler, H Du, G Banerjee… - Neurology, 2020 - AAN Enterprises
Objective To investigate whether enlarged perivascular spaces (PVS) within the basal
ganglia or deep cerebral white matter are risk factors for intracranial hemorrhage in patients …
ganglia or deep cerebral white matter are risk factors for intracranial hemorrhage in patients …
Peak width of skeletonized mean diffusivity as a marker of diffuse cerebrovascular damage
Background The peak width of skeletonized mean diffusivity (PSMD) has been proposed as
a fully automated imaging marker of relevance to cerebral small vessel disease (SVD). We …
a fully automated imaging marker of relevance to cerebral small vessel disease (SVD). We …