COVID-19 is primarily a respiratory disease but up to two thirds of hospitalised patients show
evidence of central nervous system (CNS) damage, predominantly ischaemic, in some …

The shared role of amyloid-β (Aβ) deposition in cerebral amyloid angiopathy (CAA) and
Alzheimer disease (AD) is arguably the clearest instance of crosstalk between …

Objectives The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is
considered to have potential neuroinvasiveness that might lead to acute brain disorders or …

Stroke and Alzheimer's disease (AD) are cerebral pathologies with high socioeconomic
impact that can occur together and mutually interact. Vascular factors predisposing to …

Until recent years, cerebral small vessel disease (SVD) has drawn little attention mostly
because small cerebral arteries were difficult to observe in imaging and in vivo studies …

Most neurological disorders seemingly have heterogenous pathogenesis, with overlapping
contribution of neuronal, immune and vascular mechanisms of brain injury. The perivascular …

Objective Adults with Down syndrome (DS) develop Alzheimer disease (AD) pathology by
their 5th decade. Compared with the general population, traditional vascular risks in adults …

Background and Purpose: Enlarged perivascular spaces (EPVS) have been associated with
aging, increased stroke risk, decreased cognitive function, and vascular dementia. However …

Objective To investigate whether enlarged perivascular spaces (PVS) within the basal
ganglia or deep cerebral white matter are risk factors for intracranial hemorrhage in patients …

Background The peak width of skeletonized mean diffusivity (PSMD) has been proposed as
a fully automated imaging marker of relevance to cerebral small vessel disease (SVD). We …