Allosteric control of metal-responsive transcriptional regulators in bacteria
Many transition metals are essential trace nutrients for living organisms, but they are also
cytotoxic in high concentrations. Bacteria maintain the delicate balance between metal …
cytotoxic in high concentrations. Bacteria maintain the delicate balance between metal …
Ferric uptake regulator (Fur) reversibly binds a [2Fe-2S] cluster to sense intracellular iron homeostasis in Escherichia coli
The ferric uptake regulator (Fur) is a global transcription factor that regulates intracellular
iron homeostasis in bacteria. The current hypothesis states that when the intracellular" free" …
iron homeostasis in bacteria. The current hypothesis states that when the intracellular" free" …
The transcriptional response of pathogenic Leptospira to peroxide reveals new defenses against infection-related oxidative stress
C Zavala-Alvarado, O Sismeiro, R Legendre… - PLoS …, 2020 - journals.plos.org
Pathogenic Leptospira spp. are the causative agents of the waterborne zoonotic disease
leptospirosis. Leptospira are challenged by numerous adverse conditions, including deadly …
leptospirosis. Leptospira are challenged by numerous adverse conditions, including deadly …
Heme dependent transcriptional regulation of the Pseudomonas aeruginosa tandem sRNA prrF1,F2 locus by the cytoplasmic heme binding protein PhuS
T Wilson, S Mouriño, A Wilks - bioRxiv, 2020 - biorxiv.org
Pseudomonas aeruginosa is an opportunistic pathogen requiring iron for its survival and
virulence. P. aeruginosa can acquire iron from heme via the heme assimilation system (Has) …
virulence. P. aeruginosa can acquire iron from heme via the heme assimilation system (Has) …