Revisiting the pathoetiology of multiple sclerosis: has the tail been wagging the mouse?
MK Sen, MSM Almuslehi, PJ Shortland… - Frontiers in …, 2020 - frontiersin.org
Multiple Sclerosis (MS) is traditionally considered an autoimmune-mediated demyelinating
disease, the pathoetiology of which is unknown. However, the key question remains whether …
disease, the pathoetiology of which is unknown. However, the key question remains whether …
Suppression of microglial activation and monocyte infiltration ameliorates cerebellar hemorrhage induced-brain injury and ataxia
ST Xie, AX Chen, B Song, J Fan, W Li, Z Xing… - Brain, Behavior, and …, 2020 - Elsevier
Ataxia, characterized by uncoordinated movement, is often found in patients with cerebellar
hemorrhage (CH), leading to long-term disability without effective management. Microglia …
hemorrhage (CH), leading to long-term disability without effective management. Microglia …
[HTML][HTML] The impact of quetiapine on the brain lipidome in a cuprizone-induced mouse model of schizophrenia
C Zhou, S Xue, F Xue, L Liu, J Liu, Q Ma, J Qin… - Biomedicine & …, 2020 - Elsevier
The antipsychotic effect of Quetiapine (Que) has been extensively studied and growing
evidence suggests that Que has a beneficial effect, improving cognitive functions and …
evidence suggests that Que has a beneficial effect, improving cognitive functions and …
C57BL6 mouse substrains demonstrate differences in susceptibility to the demyelinating effects of Cuprizone toxin
E O'Loughlin, B Jacob, G Zeballos, P Manfre… - bioRxiv, 2020 - biorxiv.org
Advances in our understanding of cellular functions and phenotypes in the brain rely on
technically robust experimental in vivo models with face validity towards human disease …
technically robust experimental in vivo models with face validity towards human disease …