From Interaction to Function in DNA‐Templated Supramolecular Self‐Assemblies

M Surin, S Ulrich - ChemistryOpen, 2020 - Wiley Online Library
DNA‐templated self‐assembly represents a rich and growing subset of supramolecular
chemistry where functional self‐assemblies are programmed in a versatile manner using …

[HTML][HTML] Melting temperature measurement and mesoscopic evaluation of single, double and triple DNA mismatches

LM Oliveira, AS Long, T Brown, KR Fox, G Weber - Chemical science, 2020 - pubs.rsc.org
Unlike the canonical base pairs AT and GC, the molecular properties of mismatches such as
hydrogen bonding and stacking interactions are strongly dependent on the identity of the …

Structural basis for targeting T: T mismatch with triaminotriazine-acridine conjugate induces a U-shaped head-to-head four-way junction in CTG repeat DNA

CM Chien, PC Wu, R Satange, CC Chang… - Journal of the …, 2020 - ACS Publications
The potent DNA-binding compound triaminotriazine-acridine conjugate (Z1) functions by
targeting T: T mismatches in CTG trinucleotide repeats that are responsible for causing …

Flexible RuII Schiff Base Complexes: G‐Quadruplex DNA Binding and Photo‐Induced Cancer Cell Death

M Gillard, J Weynand, H Bonnet… - … A European Journal, 2020 - Wiley Online Library
A series of new RuII Schiff base complexes built on the salphen moiety has been prepared.
This includes four flexible monometallic RuII compounds and six rigid bimetallic analogues …

[HTML][HTML] An 111 In-labelled bis-ruthenium (II) dipyridophenazine theranostic complex: mismatch DNA binding and selective radiotoxicity towards MMR-deficient cancer …

MR Gill, MG Walker, S Able, O Tietz… - Chemical …, 2020 - pubs.rsc.org
Theranostic radionuclides that emit Auger electrons (AE) can generate highly localised DNA
damage and the accompanying gamma ray emission can be used for single-photon …

Importance of base-pair opening for mismatch recognition

T Bouchal, I Durník, V Illík, K Réblová… - Nucleic Acids …, 2020 - academic.oup.com
Mismatch repair is a highly conserved cellular pathway responsible for repairing
mismatched dsDNA. Errors are detected by the MutS enzyme, which most likely senses …

The Dimeric Form of 1,3‐Diaminoisoquinoline Derivative Rescued the Mis‐splicing of Atp2a1 and Clcn1 Genes in Myotonic Dystrophy Type 1 Mouse Model

J Matsumoto, M Nakamori, T Okamoto… - … A European Journal, 2020 - Wiley Online Library
Expanded CUG repeat RNA in the dystrophia myotonia protein kinase (DMPK) gene causes
myotonic dystrophy type 1 (DM1) and sequesters RNA processing proteins, such as the …

Assembly of ruthenium complexes on double stranded DNA using mismatch binding ligands

L Ni, T Yamada, K Nakatani - Chemical Communications, 2020 - pubs.rsc.org
Herein, we show two new DNA binding small molecules, NCD-RO and NCD-RC, and their
ability to bind and selectively assemble ruthenium complexes on G–G mismatch DNA. This …

[PDF][PDF] La Hacienda de Nuestra Señora de Guadalupe San Martín alías la Lechería. Un eco en la historia del Valle de México. Siglos XVI-XVIII.

A de México - 2020 - ru.dgb.unam.mx
La historia del municipio de Cuautitlán Izcalli ha sido muy poco estudiada, resultado de la
falta de interés de los investigadores e historiadores, un mal que al parecer aqueja la zona …

[HTML][HTML] Chloro-substituted naphthyridine derivative and its conjugate with thiazole orange for highly selective fluorescence sensing of an orphan cytosine in the AP …

C Wang, Y Sato, T Sugimoto, N Teramae… - Applied Sciences, 2020 - mdpi.com
Fluorescent probes with the binding selectivity to specific structures in DNAs or RNAs have
gained much attention as useful tools for the study of nucleic acid functions. Here, chloro …