Cancer incidence and trends

MC Hulvat - Surgical Clinics, 2020 - surgical.theclinics.com
Cancer is the second leading cause of death worldwide and in North America, behind only
ischemic heart disease. 1, 2 However, a recent prospective, population-based cohort study …

[HTML][HTML] Systemic treatment of brain metastases in non-small cell lung cancer

S Page, C Milner-Watts, M Perna, U Janzic… - European Journal of …, 2020 - Elsevier
Brain metastases (BrMs) are associated with significant morbidity and are found in up to
50% of patients with advanced non-small cell lung cancer (NSCLC). Most of the literature …

[HTML][HTML] Global trends of bladder cancer incidence and mortality, and their associations with tobacco use and gross domestic product per capita

JYC Teoh, J Huang, WYK Ko, V Lok, P Choi, CF Ng… - European urology, 2020 - Elsevier
Background Bladder cancer is a major urological disease, with approximately 550 000 new
cases diagnosed in 2018. Objective We examined gender-specific incidence and mortality …

[HTML][HTML] Anti-cancer activity of biosynthesized silver nanoparticles using Avicennia marina against A549 lung cancer cells through ROS/mitochondrial damages

S Tian, K Saravanan, RA Mothana… - Saudi Journal of …, 2020 - Elsevier
Abstract The biosynthesized Ag NPs was synthesized by using marine mangrove plant
extract Avicennia marina. The synthesized Ag NPs was confirmed by various …

The major effects of health-related quality of life on 5-year survival prediction among lung cancer survivors: applications of machine learning

J Sim, YA Kim, JH Kim, JM Lee, MS Kim, YM Shim… - Scientific reports, 2020 - nature.com
The primary goal of this study was to evaluate the major roles of health-related quality of life
(HRQOL) in a 5-year lung cancer survival prediction model using machine learning …

Chemical approaches for the enhancement of porphyrin skeleton-based photodynamic therapy

Y Lin, T Zhou, R Bai, Y Xie - Journal of enzyme inhibition and …, 2020 - Taylor & Francis
With the development of photodynamic therapy (PDT), remarkable studies have been
conducted to generate photosensitisers (PSs), especially porphyrin PSs. A variety of …

CT-based radiomics for prediction of histologic subtype and metastatic disease in primary malignant lung neoplasms

JR Ferreira-Junior, M Koenigkam-Santos… - International journal of …, 2020 - Springer
Purpose As some of the most important factors for treatment decision of lung cancer (which
is the deadliest neoplasm) are staging and histology, this work aimed to associate …

Contrast-enhanced T1-weighted image radiomics of brain metastases may predict EGFR mutation status in primary lung cancer

SJ Ahn, H Kwon, JJ Yang, M Park, YJ Cha, SH Suh… - Scientific reports, 2020 - nature.com
Identification of EGFR mutations is critical to the treatment of primary lung cancer and brain
metastases (BMs). Here, we explored whether radiomic features of contrast-enhanced T1 …

Renin-angiotensin system in lung tumor and microenvironment interactions

MJ Catarata, R Ribeiro, MJ Oliveira, C Robalo Cordeiro… - Cancers, 2020 - mdpi.com
The mechanistic involvement of the renin-angiotensin system (RAS) reaches beyond
cardiovascular physiopathology. Recent knowledge pinpoints a pleiotropic role for this …

[HTML][HTML] Exosomal lncRNA PCAT-1 promotes Kras-associated chemoresistance via immunosuppressive miR-182/miR-217 signaling and p27/CDK6 regulation

K Domvri, S Petanidis, D Anestakis, K Porpodis, C Bai… - Oncotarget, 2020 - ncbi.nlm.nih.gov
Immunosuppressive chemoresistance is a major burden in lung cancer. Recent data reveal
that long noncoding RNAs (lncRNAs) present in the lung tumor microenvironment are …