The Kinin B2 receptor (B2R) is classically involved in vasodilation and inflammatory
responses. However, through the observation of hypoglycemic effects of Angiotensin-I …

Kinins are mediators of pain and inflammation and evidence suggests that the inducible
kinin B1 receptor (B1R) is involved in neuropathic pain (NP). This study investigates whether …

Background and Purpose The entire kallikrein–kinin system is present in the skin, and it is
thought to exert a relevant role in cutaneous diseases, including psoriasis. The present …

Our recent study has implicated bradykinin (BK) signaling as being of pathogenic
importance in lupus. This study aims to investigate the biomarker potential of BK peptides …

Background In sepsis, the endothelial barrier becomes incompetent, with the leaking of
plasma into interstitial tissues. VE-cadherin, an adherens junction protein, is the gatekeeper …

The transient receptor potential (TRP) superfamily is composed of 28 non-selective cation
channels, which have been implicated in a myriad of physiological processes ranging from …

Traumatic brain injury (TBI) is a cerebral insult with high morbidity and mortality. In past
decades, TBI imposed a heavy socioeconomic burden on society, leading to relevant public …