For much of the last century, our knowledge regarding the pancreas in type 1 and type 2
diabetes was largely derived from autopsy studies of individuals with these disorders or …

Oleanolic acid (OA) and its derivatives are widely found in diverse plants and are naturally
effective pentacyclic triterpenoid compounds with broad prophylactic and therapeutic roles …

Aims Recent findings have instituted the role of hyperglycemia-related AGE/RAGE and NF-
κB in instigating reactive oxygen species (ROS) mediated mitochondrial dysfunction and …

Diabetes mellitus, also known simply as diabetes, has been described as a chronic and
complex endocrine metabolic disorder that is a leading cause of death across the globe. It is …

Pancreatic cancer (PC) is a highly fatal cancer with currently limited opportunities for early
detection and effective treatment. Modifiable factors may offer pathways for primary …

Early prediction of target patients at high risk of developing Type 2 diabetes (T2D) plays a
significant role in preventing the onset of overt disease and its associated comorbidities …

Despite the increasing use of protoplasts in plant biotechnology research, shoot
regeneration from protoplasts remains challenging. In this study, we investigated the factors …

Ganoderma lucidum is used widely in oriental medicine to treat obesity and metabolic
diseases. Bioactive substances extracted from G. lucidum have been shown to ameliorate …

Recent preclinical and clinical studies have indicated that the galanin peptide family may
regulate glucose metabolism and alleviate insulin resistance, which diminishes the …

Aims/hypothesis The aim was to investigate whether an intensive lifestyle intervention, with
high volumes of exercise, improves beta cell function and to explore the role of low-grade …