[HTML][HTML] Overexpression of GSDMC is a prognostic factor for predicting a poor outcome in lung adenocarcinoma
J Wei, Z Xu, X Chen, X Wang… - Molecular …, 2020 - spandidos-publications.com
The gasdermin (GSDM) superfamily has been demonstrated to consist of several important
molecules that modulate multifunctional signal processes, such as cell pyroptosis. In this …
molecules that modulate multifunctional signal processes, such as cell pyroptosis. In this …
The N6‐methyladenosine (m6A) erasers alkylation repair homologue 5 (ALKBH5) and fat mass and obesity‐associated protein (FTO) are prognostic biomarkers in …
A Strick, F von Hagen, L Gundert, N Klümper… - BJU …, 2020 - Wiley Online Library
Objectives To comprehensively investigate the role of the N6‐methyladenosine (m6A)
erasers ALKBH5 and FTO in clear cell renal cell carcinoma (ccRCC), other RCC subtypes …
erasers ALKBH5 and FTO in clear cell renal cell carcinoma (ccRCC), other RCC subtypes …
DNA methylation biomarkers for nasopharyngeal carcinoma
B Han, X Yang, P Zhang, Y Zhang, Y Tu, Z He, Y Li… - PLoS …, 2020 - journals.plos.org
Background Aberrant methylation of DNA plays an important role in the pathogenesis of
nasopharyngeal carcinoma (NPC). In the current study, we aimed to integrate three cohorts …
nasopharyngeal carcinoma (NPC). In the current study, we aimed to integrate three cohorts …
Hypomethylation of PlncRNA-1 promoter enhances bladder cancer progression through the miR-136-5p/Smad3 axis
W Kang, Q Wang, Y Dai, H Wang, M Wang… - Cell death & …, 2020 - nature.com
Apart from being potential prognostic biomarkers and therapeutic targets, long non-coding
RNAs (lncRNAs) modulate the development and progression of multiple cancers. PlncRNA …
RNAs (lncRNAs) modulate the development and progression of multiple cancers. PlncRNA …
Multi-omics analysis identifying key biomarkers in ovarian cancer
JY Li, CJ Li, LT Lin, KH Tsui - Cancer Control, 2020 - journals.sagepub.com
Ovarian cancer is one of the most common malignant tumors. Here, we aimed to study the
expression and function of the CREB1 gene in ovarian cancer via the bioinformatic analyses …
expression and function of the CREB1 gene in ovarian cancer via the bioinformatic analyses …
Selenium-binding protein 1 transcriptionally activates p21 expression via p53-independent mechanism and its frequent reduction associates with poor prognosis in …
Y Wang, W Zhu, X Chen, G Wei, G Jiang… - Journal of translational …, 2020 - Springer
Background Recent studies have shown that selenium-binding protein 1 (SELENBP1) is
significantly down-regulated in a variety of solid tumors. Nevertheless, the clinical relevance …
significantly down-regulated in a variety of solid tumors. Nevertheless, the clinical relevance …
LOXL2 expression status is correlated with molecular characterizations of cervical carcinoma and associated with poor cancer survival via epithelial-mesenchymal …
C Cao, S Lin, W Zhi, C Lazare, Y Meng, P Wu… - Frontiers in …, 2020 - frontiersin.org
As molecular analyses based on high-throughput sequencing have developed, the
molecular classification of cancer has facilitated clinical work. The aim of the present study …
molecular classification of cancer has facilitated clinical work. The aim of the present study …
Melanoma stem cell-like phenotype and significant suppression of immune response within a tumor are regulated by TRIM28 protein
P Czerwinska, AM Jaworska, NA Wlodarczyk… - Cancers, 2020 - mdpi.com
Simple Summary A growing body of evidence indicates that stem cell-associated molecular
features, collectively known as stemness, are biologically important in cancer development …
features, collectively known as stemness, are biologically important in cancer development …
Comprehensive analysis of autophagy‐related prognostic genes in breast cancer
J Lai, B Chen, H Mok, G Zhang… - Journal of Cellular and …, 2020 - Wiley Online Library
Accumulating evidence revealed that autophagy played vital roles in breast cancer (BC)
progression. Thus, the aim of this study was to investigate the prognostic value of autophagy …
progression. Thus, the aim of this study was to investigate the prognostic value of autophagy …
The study of sarcoma microenvironment heterogeneity associated with prognosis based on an immunogenomic landscape analysis
J Deng, W Zeng, W Kong, Y Shi, X Mou - Frontiers in Bioengineering …, 2020 - frontiersin.org
Microenvironment-driven tumor heterogeneity causes the limitation of immunotherapy of
sarcomas. Nonetheless, systematical studies of various molecular levels can enhance the …
sarcomas. Nonetheless, systematical studies of various molecular levels can enhance the …