The anatomy and physiology of the microcirculation in human skin are complex. Normal
cutaneous microcirculation is organized in two parallel plexuses with capillary loops …

Diabetes is a worldwide health issue closely associated with cardiovascular events. Given
the pandemic of obesity, the identification of the basic underpinnings of vascular disease is …

Previous studies indicate that sex-related differences exist in the regulation of cutaneous
vasodilation, however, the mechanisms remain unresolved. We assessed if sex-differences …

Post-occlusive reactive hyperemia (PORH) is a key feature of physiological vasomotion to
appropriately match the supply/demand ratio of tissues. This adaptive mechanism is …

One week of daily remote ischemic preconditioning (RIPC) improves cutaneous vasodilatory
(VD) function. However, the underlying mechanisms and the number of sessions needed to …

Endothelial nitric oxide synthase (eNOS) malfunctioning has been proposed to contribute to
the endothelial damage produced by cigarette. Besides eNOS, neuronal NOS (nNOS) is …

In humans, the primary response to increasing internal temperature is increased cutaneous
blood flow along with sweating. These reflexes facilitate heat dissipation to the environment …

Compared with hospital based therapies, peritoneal dialysis (PD) offers many advantages to
patients with end stage renal disease in terms of greater autonomy and independence in …