Identification of Key Small Non‐Coding MicroRNAs Controlling Pacemaker Mechanisms in the Human Sinus Node

M Petkova, AJ Atkinson, J Yanni, L Stuart… - Journal of the …, 2020 - Am Heart Assoc
Background The sinus node (SN) is the primary pacemaker of the heart. SN myocytes
possess distinctive action potential morphology with spontaneous diastolic depolarization …

Simultaneous Endo‐Epicardial Mapping of the Human Right Atrium: Unraveling Atrial Excitation

RK Kharbanda, P Knops… - Journal of the …, 2020 - Am Heart Assoc
Background The significance of endo‐epicardial asynchrony (EEA) and atrial conduction
block (CB), which play an important role in the pathophysiology of atrial fibrillation (AF) …

A novel method with which to visualize the human sinuatrial node: Application for a better understanding of the gross anatomy of this part of the conduction system

K Nooma, T Saga, J Iwanaga, Y Tabira… - Clinical …, 2020 - Wiley Online Library
For various clinical/surgical procedures, it is important to accurately understand the location
of the sinuatrial node (SAN). Therefore, this study's goal was to develop a new and simple …

Asymmetric properties of heart rate microstructure

P Guzik, J Piskorski - Journal of Medical Science, 2020 - jms.ump.edu.pl
The duration of each cardiac cycle is measured on an ECG as the distance between the
peaks of consecutive R waves (RR interval), with the inverse value corresponding to the …

[HTML][HTML] Sinus node dysfunction characterized by reduction only in maximum heart rate during exercise after superior vena cava isolation in atrial fibrillation catheter …

T Hayashi, A Mizukami, S Kuroda, A Matsumura… - HeartRhythm Case …, 2020 - Elsevier
The superior vena cava (SVC) is one of the most common sites of non–pulmonary vein (PV)
foci in atrial fibrillation (AF), and SVC isolation is an established ablation strategy for AF …

Localization of the sinoatrial and atrioventricular nodal region in neonatal and juvenile ovine hearts

JK Johnson, BK Cottle, A Mondal, R Hitchcock… - Plos one, 2020 - journals.plos.org
Localization of the components of the cardiac conduction system (CCS) is essential for many
therapeutic procedures in cardiac surgery and interventional cardiology. While histological …

[PDF][PDF] Understanding altered intrinsic heart rate in type 2 diabetes

S Parveen - University of Otago, 2020 - ourarchive.otago.ac.nz
Heart rate (HR) is generated by sinoatrial node (SAN) intrinsic pacemaking and modulated
by autonomic innervation. Within the SAN, intrinsic (ex vivo) HR is determined by the mutual …

[PDF][PDF] A computational based approach for non-invasive localization of atrial ectopic foci

EJ Godoy - 2020 - uv.es
Abstract/Resumen Abstract Atrial arrhythmias are the most common cardiac arrhythmia,
affecting six million people in Europe and imposing a huge healthcare burden on society …

The Sick Sinus Syndrome

JA Gomes, JA Gomes - Heart Rhythm Disorders: History, Mechanisms …, 2020 - Springer
In this chapter the author discusses the anatomy and physiology of the sinus node; the
historical aspects of the sick sinus syndrome (SSS); its clinical manifestations, etiology …

Indications for permanent cardiac pacing

RM John - Cardiac Pacing and ICDs, 2020 - Wiley Online Library
Defects of cardiac impulse generation and conduction can occur at various levels in the
cardiac conduction system. Conduction disorders that lead to important bradycardia or …