The solid tumor microenvironment possesses a hypoxic condition, which promotes
aggressiveness and resistance to therapies. Hypoxic tumor cells undergo broadly metabolic …

Atherosclerosis (AS), a typical chronic inflammatory vascular disease, is the main
pathological basis of ischemic cardio/cerebrovascular disease (CVD). Long‐term …

Objective To assess geniposide's effects in New Zealand rabbits with high-fat diet induced
atherosclerosis and to explore the underpinning mechanisms. Materials and methods Aorta …

Atherosclerosis is a major reason for the high morbidity and mortality of cardiovascular
diseases. Macrophage inflammation and foam cell formation are the key pathological …

Endothelial cell damage caused by oxidative stress is widely considered to be a triggering
event in atherosclerosis (AS). However, the specific effect elicited by autophagy in …

Background Rapamycin is known to be effective in suppressing senescence and the
senescence-associated secretory phenotype (SASP). Therefore, it is highly expected to …

Cardiovascular disease (CVD) remains the leading cause of morbidity and mortality
worldwide. Atherosclerosis (AS) is a major cause of CVD. Oxidative stress, endothelial …

Transient receptor potential vanilloid subfamily member 1 (TRPV1) is a nonselective cation
channel, that is mainly distributed in sensory nerve endings and can release a variety of …

Background This study focused on the roles of lncRNA THRIL in coronary atherosclerotic
heart disease (CAD) through regulating AKT signaling pathway and directly interacting with …

Atherosclerosis (AS) is a chronic progressive disease caused by injury and functional
changes in vascular smooth muscle cells (VSMCs). Long non‑coding RNAs (lncRNAs) are …