Malaria, caused by apicomplexan parasite, is an old disease and continues to be a major
public health threat in many countries. This article aims to present different aspects of …

Malaria continues to be a global health threat, affecting approximately 219 million people in
2018 alone. The recurrent development of resistance to existing antimalarials means that …

Microscopy and rapid diagnostic tests (RDTs) are the main diagnostic tools for malaria but
fail to detect low-density parasitemias that are important for maintaining malaria …

Malaria puts at risk nearly half the world's population and causes high mortality in sub-
Saharan Africa, while drug resistance threatens current therapies. The pyrimidine …

Malaria volunteer infection studies (VISs) accelerate new drug and vaccine development. In
the induced blood-stage malaria (IBSM) model, volunteers are inoculated with erythrocytes …

Background Growth rate of malaria parasites in the blood of infected subjects is an important
measure of efficacy of drugs and vaccines. Methods We used log-linear and sine-wave …

Objective Ivermectin is safe and widely used for treating helminth infections. It also kills
arthropods feeding on treated subjects, including malaria vectors. Thus, ivermectin mass …

Dihydroorotate dehydrogenase (DHODH) is a mitochondrial monotopic membrane protein
that plays an essential role in the pyrimidine de novo biosynthesis and electron transport …

Community-acquired acute kidney injury (CA-AKI) is the dominant form of AKI encountered
in developing countries in Asia. Economic disparities, variations in access to health care …

Malaria is an old disease and continues to be a major health problem in many countries. In
spite of decrement in morbidity and mortality due to malaria, the transmission is still active …