[HTML][HTML] Role of human leukocyte antigen system as a predictive biomarker for checkpoint-based immunotherapy in cancer patients
Recent advances in cancer immunotherapy have clearly shown that checkpoint-based
immunotherapy is effective in a small subgroup of cancer patients. However, no effective …
immunotherapy is effective in a small subgroup of cancer patients. However, no effective …
[HTML][HTML] Leukocyte immunoglobulin-like receptors (LILRs) on human neutrophils: modulators of infection and immunity
AL Lewis Marffy, AJ McCarthy - Frontiers in immunology, 2020 - frontiersin.org
Neutrophils have a crucial role in defense against microbes. Immune receptors allow
neutrophils to sense their environment, with many receptors functioning to recognize signs …
neutrophils to sense their environment, with many receptors functioning to recognize signs …
Comparative genetics of the major histocompatibility complex in humans and nonhuman primates
CMC Heijmans, NG de Groot… - International Journal of …, 2020 - Wiley Online Library
The major histocompatibility complex (MHC) is one of the most gene‐dense regions of the
mammalian genome. Multiple genes within the human MHC (HLA) show extensive …
mammalian genome. Multiple genes within the human MHC (HLA) show extensive …
A role for both HLA-F and HLA-G in reproduction and during pregnancy?
G Persson, N Jørgensen, LL Nilsson, LHJ Andersen… - Human immunology, 2020 - Elsevier
The human major histocompatibility complex includes a group of non-classical HLA class I
genes, HLA-E,-F and-G. While nearly all focus since the discovery of these class Ib …
genes, HLA-E,-F and-G. While nearly all focus since the discovery of these class Ib …
[HTML][HTML] HLA-G and HLA-F protein isoform expression in breast cancer patients receiving neoadjuvant treatment
FM Wuerfel, H Huebner, L Häberle, P Gass, A Hein… - Scientific reports, 2020 - nature.com
The immunosuppressive human leukocyte antigens HLA-G and HLA-F are expressed on
trophoblast and malignant cells. Four membrane-bound and three soluble HLA-G protein …
trophoblast and malignant cells. Four membrane-bound and three soluble HLA-G protein …
Variation in the HLA-F gene locus with functional impact is associated with pregnancy success and time-to-pregnancy after fertility treatment
CH Langkilde, LL Nilsson, N Jørgensen… - Human …, 2020 - academic.oup.com
STUDY QUESTION The aim of this study was to investigate a possible influence of three
single nucleotide polymorphisms (SNPs) in the HLA-F gene locus on time-to-pregnancy and …
single nucleotide polymorphisms (SNPs) in the HLA-F gene locus on time-to-pregnancy and …
[HTML][HTML] The potential of soluble human leukocyte antigen molecules for early cancer detection and therapeutic vaccine design
AL Kessler, MJ Bruno, SI Buschow - Vaccines, 2020 - mdpi.com
Human leukocyte antigen (HLA) molecules are essential for anti-tumor immunity, as they
display tumor-derived peptides to drive tumor eradication by cytotoxic T lymphocytes. HLA …
display tumor-derived peptides to drive tumor eradication by cytotoxic T lymphocytes. HLA …
Leukocyte immunoglobulin-like receptor subfamily B member 1 potentially acts as a diagnostic and prognostic target in certain subtypes of adenocarcinoma
Abstract Background Leukocyte immunoglobulin (Ig)-like receptor subfamily B member 1
(LILRB1) involves in the occurrence and development of various tumors through transmitting …
(LILRB1) involves in the occurrence and development of various tumors through transmitting …
[HTML][HTML] Evolution of HLA-F and its orthologues in primate species: a complex tale of conservation, diversification and inactivation
N Otting, NG De Groot, RE Bontrop - Immunogenetics, 2020 - Springer
HLA-F represents one of the nonclassical MHC class I molecules in humans. Its main
characteristics involve low levels of polymorphism in combination with a restricted tissue …
characteristics involve low levels of polymorphism in combination with a restricted tissue …
[HTML][HTML] The loss of HLA-F/KIR3DS1 ligation is mediated by hemoglobin peptides
GGT Hò, W Hiemisch, A Pich, GMN Behrens… - International Journal of …, 2020 - mdpi.com
The human leukocyte antigen (HLA)-Ib molecule, HLA-F, is known as a CD4+ T-cell protein
and mediator of HIV progression. While HLA-Ia molecules do not have the chance to select …
and mediator of HIV progression. While HLA-Ia molecules do not have the chance to select …