Alveolar dynamics and beyond–the importance of surfactant protein C and cholesterol in lung homeostasis and fibrosis
K Sehlmeyer, J Ruwisch, N Roldan… - Frontiers in …, 2020 - frontiersin.org
Surfactant protein C (SP-C) is an important player in enhancing the interfacial adsorption of
lung surfactant lipid films to the alveolar air-liquid interface. Doing so, surface tension drops …
lung surfactant lipid films to the alveolar air-liquid interface. Doing so, surface tension drops …
Genetics of Idiopathic Pulmonary Fibrosis
SK Mathai, DA Schwartz - Precision in Pulmonary, Critical Care, and …, 2020 - Springer
In the last two decades, there has been significant growth in our understanding of the
genetics underlying idiopathic pulmonary fibrosis (IPF), a relentlessly progressive, incurable …
genetics underlying idiopathic pulmonary fibrosis (IPF), a relentlessly progressive, incurable …
Development of novel synthetic lung surfactants for treatment of respiratory distress syndrome
O Basabe Burgos - 2020 - openarchive.ki.se
Pulmonary surfactant is a complex mixture of lipids and specific proteins found in the alveoli
and its main role is to reduce the surface tension of the alveolar air/water interface, thereby …
and its main role is to reduce the surface tension of the alveolar air/water interface, thereby …
Genetic determinants of interstitial lung diseases
SK Mathai, DA Schwartz, R Borie - … and Rimoin's Principles and Practice of …, 2020 - Elsevier
Interstitial lung diseases (ILDs) are a set of heterogeneous lung diseases characterized by
inflammation and, in some cases, fibrosis of the space between alveoli. These lung …
inflammation and, in some cases, fibrosis of the space between alveoli. These lung …
Development of Novel Synthetic Lung Surfactants for Treatment of Respiratory Distress Syndrome
OB Burgos - 2020 - search.proquest.com
Pulmonary surfactant is a complex mixture of lipids and specific proteins found in the alveoli
and its main role is to reduce the surface tension of the alveolar air/water interface, thereby …
and its main role is to reduce the surface tension of the alveolar air/water interface, thereby …
Recent Insights into In Utero Gene Editing, Checkpoint Inhibitors, and Polymorphonuclear Extracellular Vesicles
A O'Reilly, A Sahadevan, W Shah… - American Journal of …, 2020 - atsjournals.org
In their recent study, Alapati and colleagues (1) demonstrated that CRISPR-Cas9 can be
used to perform gene editing through in utero intra-amniotic delivery during fetal …
used to perform gene editing through in utero intra-amniotic delivery during fetal …
Genetic testing for rare pediatric lung disorders: The promise and the pitfalls
LM Nogee - Pediatric Investigation, 2020 - mednexus.org
Development. supporting that SFTPC p. Ile73Thr mutation is pathogenic are robust. There
are multiple reports of patients with a consistent phenotype with this mutation, while it is …
are multiple reports of patients with a consistent phenotype with this mutation, while it is …