[HTML][HTML] Recent advances in meningioma immunogenetics
M Al-Rashed, K Foshay, M Abedalthagafi - Frontiers in Oncology, 2020 - frontiersin.org
Meningiomas are relatively common, and typically benign intracranial tumors, which in many
cases can be cured by surgical resection. However, less prevalent, high grade …
cases can be cured by surgical resection. However, less prevalent, high grade …
Multiplatform genomic profiling and magnetic resonance imaging identify mechanisms underlying intratumor heterogeneity in meningioma
ST Magill, HN Vasudevan, K Seo… - Nature …, 2020 - nature.com
Meningiomas are the most common primary intracranial tumors, but the molecular drivers of
meningioma tumorigenesis are poorly understood. We hypothesized that investigating …
meningioma tumorigenesis are poorly understood. We hypothesized that investigating …
Parasellar meningiomas
Parasellar spaces remain particularly singular, comprising the most important neurovascular
structures such as the internal carotid artery and optic, oculomotor, and trigeminal nerves …
structures such as the internal carotid artery and optic, oculomotor, and trigeminal nerves …
Forkhead box M1 (FOXM1) transcription factor is a key oncogenic driver of aggressive human meningioma progression
H Kim, KJ Park, BK Ryu, DH Park… - Neuropathology and …, 2020 - Wiley Online Library
Aims Aggressive meningioma remains incurable with neither chemo‐nor targeted therapies
proven effective, largely due to unidentified genetic alterations and/or aberrant oncogenic …
proven effective, largely due to unidentified genetic alterations and/or aberrant oncogenic …
Pediatric meningioma: a clinicopathologic and molecular study with potential grading implications
A Toland, SN McNulty, M Pekmezci… - Brain …, 2020 - Wiley Online Library
Meningiomas are common in adults (~ 35% of brain tumors) but rare in children, where they
exhibit unique clinical, pathological and molecular features compared to adult counterparts …
exhibit unique clinical, pathological and molecular features compared to adult counterparts …
[HTML][HTML] Comprehending meningioma signaling cascades using multipronged proteomics approaches & targeted validation of potential markers
Meningiomas are one of the most prevalent primary brain tumors. Our study aims to obtain
mechanistic insights of meningioma pathobiology using mass spectrometry-based label-free …
mechanistic insights of meningioma pathobiology using mass spectrometry-based label-free …
[HTML][HTML] High copy-number variation burdens in cranial meningiomas from patients with diverse clinical phenotypes characterized by hot genomic structure changes
J Ma, Y Hong, W Chen, D Li, K Tian, K Wang… - Frontiers in …, 2020 - frontiersin.org
Meningiomas, as the most common primary tumor of the central nervous system, are known
to harbor genomic aberrations that associate with clinical phenotypes. Here we performed …
to harbor genomic aberrations that associate with clinical phenotypes. Here we performed …
WHO grade I meningiomas: classification-tree for prognostic factors of survival
JM Lemée, H Joswig, M Da Broi, MV Corniola… - Neurosurgical …, 2020 - Springer
Abstract World Health Organization (WHO) grade I meningiomas are intracranial
extracerebral tumors, in which microsurgery as a stand-alone therapy provides high rates of …
extracerebral tumors, in which microsurgery as a stand-alone therapy provides high rates of …
Expression and clinical significance of immune checkpoint regulator B7-H3 (CD276) in human meningioma
J Deng, M Ma, D Wang, H Zhu, L Hua, S Sun, H Chen… - World neurosurgery, 2020 - Elsevier
Background The high expression across multiple tumor types and restricted expression in
normal tissues make B7-H3 an attractive target for immunotherapy. So far, little is known …
normal tissues make B7-H3 an attractive target for immunotherapy. So far, little is known …
Meningioma epigenetic grouping reveals biologic drivers and therapeutic vulnerabilities
Meningiomas arising from the meningothelial central nervous system lining are the most
common primary intracranial tumors, and a significant cause of neurologic morbidity and …
common primary intracranial tumors, and a significant cause of neurologic morbidity and …