Background A proposed mechanism of chronic pain is dysregulation between the main
inhibitory (GABA) and excitatory (glutamate) neurometabolites of the central nervous system …

Cerebral metabolism is tightly regulated and fundamental for healthy neurological function.
There is increasing evidence that alterations in this metabolism may be a precursor and …

There is growing interest in the therapeutic utility of psychedelic substances, like psilocybin,
for disorders characterized by distortions of the self-experience, like depression …

Background Processing and quantitative analysis of magnetic resonance spectroscopy
(MRS) data are far from standardized and require interfacing with third-party software. Here …

Behavioural disinhibition is a common feature of the syndromes associated with
frontotemporal lobar degeneration (FTLD). It is associated with high morbidity and lacks …

Quantitative mapping of the in vivo dynamics of cellular metabolism via non-invasive
imaging contributes to our understanding of the initiation and progression of diseases …

Evidence points toward a relationship between longer duration of untreated psychosis
(DUP) and worse long-term outcomes in patients with first episode psychosis (FEP), but the …

Mitochondrial dysfunction is postulated to be central to amyotrophic lateral sclerosis (ALS)
pathophysiology. Evidence comes primarily from disease models and conclusive data to …

Objectives Successful neurosurgical intervention in gliomas depends on the precision of the
preoperative definition of the tumor and its margins since a safe maximum resection …

To understand neurochemical brain responses to pain, proton magnetic resonance
spectroscopy (1H-MRS) is used in humans in vivo to examine various metabolites. Recent …