[HTML][HTML] Preterm birth and sustained inflammation: consequences for the neonate

A Humberg, I Fortmann, B Siller, MV Kopp… - Seminars in …, 2020 - Springer
Almost half of all preterm births are caused or triggered by an inflammatory process at the
feto-maternal interface resulting in preterm labor or rupture of membranes with or without …

Probiotics to prevent necrotising enterocolitis in very preterm or very low birth weight infants

S Sharif, N Meader, SJ Oddie… - Cochrane Database …, 2020 - cochranelibrary.com
Background Intestinal dysbiosis may contribute to the pathogenesis of necrotising
enterocolitis (NEC) in very preterm or very low birth weight infants. Dietary supplementation …

[HTML][HTML] The infant gut microbiome as a microbial organ influencing host well-being

F Turroni, C Milani, S Duranti, GA Lugli… - Italian journal of …, 2020 - Springer
Initial establishment of the human gut microbiota is generally believed to occur immediately
following birth, involving key gut commensals such as bifidobacteria that are acquired from …

[HTML][HTML] The role of human milk oligosaccharides and probiotics on the neonatal microbiome and risk of necrotizing enterocolitis: a narrative review

LS Nolan, JM Rimer, M Good - Nutrients, 2020 - mdpi.com
Preterm infants are a vulnerable population at risk of intestinal dysbiosis. The newborn
microbiome is dominated by Bifidobacterium species, though abnormal microbial …

Bacteriophage-mediated manipulation of the gut microbiome–promises and presents limitations

TS Rasmussen, AK Koefoed… - FEMS Microbiology …, 2020 - academic.oup.com
Gut microbiome (GM) composition and function are linked to human health and disease, and
routes for manipulating the GM have become an area of intense research. Due to its high …

[HTML][HTML] Emerging biomarkers for prediction and early diagnosis of necrotizing enterocolitis in the era of metabolomics and proteomics

E Agakidou, C Agakidis, H Gika, K Sarafidis - Frontiers in Pediatrics, 2020 - frontiersin.org
Necrotizing Enterocolitis (NEC) is a catastrophic disease affecting predominantly premature
infants and is characterized by high mortality and serious long-term consequences …

Effect of intrapartum antibiotics on the intestinal microbiota of infants: a systematic review

P Zimmermann, N Curtis - Archives of Disease in Childhood-Fetal and …, 2020 - fn.bmj.com
Introduction The use of intrapartum antibiotic prophylaxis (IAP) has become common
practice in obstetric medicine and is used in up to 40% of deliveries. Despite its benefits, the …

An overview of systematic reviews of randomized-controlled trials for preventing necrotizing enterocolitis in preterm infants

T Xiong, A Maheshwari, J Neu, A Ei-Saie, M Pammi - Neonatology, 2020 - karger.com
Necrotizing enterocolitis (NEC) remains a major cause for neonatal mortality and morbidity
in preterm infants. The purpose of this review was to summarize evidence from systematic …

Stem cell therapy for preventing neonatal diseases in the 21st century: current understanding and challenges

CR Nitkin, J Rajasingh, C Pisano, GE Besner… - Pediatric …, 2020 - nature.com
Diseases of the preterm newborn such as bronchopulmonary dysplasia, necrotizing
enterocolitis, cerebral palsy, and hypoxic-ischemic encephalopathy continue to be major …

[HTML][HTML] Exploring the role of gut bacteria in health and disease in preterm neonates

JKF Lee, LT Hern Tan, A Ramadas… - International journal of …, 2020 - mdpi.com
The mortality rate of very preterm infants with birth weight< 1500 g is as high as 15%. The
survivors till discharge have a high incidence of significant morbidity, which includes …