Nanomaterials to relieve tumor hypoxia for enhanced photodynamic therapy

C Zhang, WJ Qin, XF Bai, XZ Zhang - Nano Today, 2020 - Elsevier
Photodynamic therapy (PDT) shows great potential for tumor treatment owing to its high
spatiotemporal selectivity, minimal invasiveness and patient compliance. However, the …

Self-amplification of tumor oxidative stress with degradable metallic complexes for synergistic cascade tumor therapy

G Chen, Y Yang, Q Xu, M Ling, H Lin, W Ma, R Sun… - Nano …, 2020 - ACS Publications
The ferroptosis effect has been illuminated with a clear Fenton reaction mechanism that
converts endogenous hydrogen peroxide (H2O2) into highly oxidative hydroxyl radicals …

Effects of ultrasound frequency mode on myofibrillar protein structure and emulsifying properties

J Chen, X Zhang, S Xue, X Xu - International Journal of Biological …, 2020 - Elsevier
In this study, different ultrasound frequencies, including 20 kHz, 23 kHz, and 20/23 kHz,
were applied for the treatment of myofibrillar protein (MP) with different protein …

Polymer-based nanomaterials for noninvasive cancer photothermal therapy

C Yu, L Xu, Y Zhang, PS Timashev… - ACS Applied Polymer …, 2020 - ACS Publications
Over the past decade, noninvasive photothermal therapy (PTT) has been intensively
investigated for the treatment of tumors. In contrast to the traditional therapies, PTT has high …

Efficient synthesis of folate-conjugated hollow polymeric capsules for accurate drug delivery to cancer cells

W Song, Y Zhang, DG Yu, CH Tran, M Wang… - …, 2020 - ACS Publications
This study presents an efficient and systematic approach to synthesize bioapplicable porous
hollow polymeric capsules (HPCs). The hydroxyl-functionalized nanoporous polymers with …

Photocatalytic materials: an apollo's arrow to tumor cells

W Li, C Wang, Y Yao, C Wu, W Luo, Z Zou - Trends in Chemistry, 2020 - cell.com
Photo-therapeutics have attracted increasing attention for the treatment of tumors because of
their controllable and tunable nature and low potential for side effects. Photocatalytic …

Emission wavelength switchable carbon dots combined with biomimetic inorganic nanozymes for a two-photon fluorescence immunoassay

Y Zhan, S Yang, F Luo, L Guo, Y Zeng… - ACS applied materials …, 2020 - ACS Publications
In this work, o-phenylenediamine is utilized as a precursor to synthesize the fluorescent
emission wavelength switchable carbon dots (o-CDs). Our investigation reveals that ferrous …

[HTML][HTML] Synergy of tumor microenvironment remodeling and autophagy inhibition to sensitize radiation for bladder cancer treatment

T Lin, Q Zhang, A Yuan, B Wang, F Zhang, Y Ding… - Theranostics, 2020 - ncbi.nlm.nih.gov
Tumor hypoxia, acidosis, and excessive reactive oxygen species (ROS) were the main
characteristics of the bladder tumor microenvironment (TME), and abnormal TME led to …

Ultrasound and near-infrared light dual-triggered upconversion zeolite-based nanocomposite for hyperthermia-enhanced multimodal melanoma therapy via a precise …

L Zheng, Y Zhang, H Lin, S Kang, Y Li… - … applied materials & …, 2020 - ACS Publications
High reactive oxygen species (ROS) generation efficiency and induction of targeted cell
apoptosis are recognized as key objectives to achieve a highly efficient strategy for cancer …

Facile synthesis of melanin-dye nanoagent for NIR-II fluorescence/photoacoustic imaging-guided photothermal therapy

J Sun, W Cai, Y Sun, C Guo… - International Journal of …, 2020 - Taylor & Francis
Background Laryngeal cancer is the second most common type of primary epithelial
malignant tumor in the head and neck region, and the development of therapies that are …