The Genetic Mechanisms Driving Diversification of the KIR Gene Cluster in Primates

J Bruijnesteijn, NG De Groot, RE Bontrop - Frontiers in Immunology, 2020 - frontiersin.org
The activity and function of natural killer (NK) cells are modulated through the interactions of
multiple receptor families, of which some recognize MHC class I molecules. The high level of …

Diversity of KIRs in invasive breast cancer patients and healthy controls along with the clinical significance in ER/PR/HER2+ patients

M Hematian Larki, S Barani, AR Talei, A Ghaderi - Genes & Immunity, 2020 - nature.com
Killer cell immunoglobulin-like receptors (KIR) consists of activating and inhibitory genes are
essential for natural killer cell education. To determine the association of KIR s with …