Tumor immune microenvironment in head and neck cancers

SMY Chen, AL Krinsky, RA Woolaver… - Molecular …, 2020 - Wiley Online Library
Head and neck cancers are a heterogeneous group of tumors that are highly aggressive
and collectively represent the sixth most common cancer worldwide. Ninety percent of head …

[HTML][HTML] Metastatic disease in head & neck oncology

P Pisani, M Airoldi, A Allais, PA Valletti… - Acta …, 2020 - ncbi.nlm.nih.gov
The head and neck district represents one of the most frequent sites of cancer, and the
percentage of metastases is very high in both loco-regional and distant areas. Prognosis …

[HTML][HTML] Cancer-associated fibroblast density, prognostic characteristics, and recurrence in head and neck squamous cell carcinoma: a meta-analysis

AM Knops, A South, U Rodeck… - Frontiers in …, 2020 - frontiersin.org
Introduction The progression and clinical course of head and neck squamous cell carcinoma
(HNSCC) relies on complex interactions between cancer and stromal cells in the tumor …

[HTML][HTML] Identification of prognostic immune-related genes in the tumor microenvironment of endometrial cancer

P Chen, Y Yang, Y Zhang, S Jiang, X Li… - Aging (Albany NY), 2020 - ncbi.nlm.nih.gov
Endometrial cancer (EC) is one of the most common gynecologic malignancies. To identify
potential prognostic biomarkers for EC, we analyzed the relationship between the EC tumor …

[HTML][HTML] Tumor microenvironment and immunotherapy response in head and neck cancer

P Economopoulou, I Kotsantis, A Psyrri - Cancers, 2020 - mdpi.com
Simple Summary Immunotherapy has revolutionized cancer treatment and has been
integrated in the treatment algorithm of metastatic head and neck cancer. Despite robust …

Tumour microenvironment in skin carcinogenesis

SR Georgescu, M Tampa, CI Mitran, MI Mitran… - … Brain to the Skin–Part A, 2020 - Springer
Tumour microenvironment is a complex system comprising cells and molecules that will
provide the necessary conditions for tumour development and progression. Cells residing in …

Erianin induces apoptosis and autophagy in oral squamous cell carcinoma cells

YT Chen, MJ Hsieh, PN Chen, CJ Weng… - The American journal …, 2020 - World Scientific
Oral squamous cell carcinoma (OSCC) is a leading cause of cancer-related deaths
worldwide. It has a very poor prognosis with over a 5-year survival rate of only 50%. Thus, it …

[HTML][HTML] Preclinical models of head and neck squamous cell carcinoma for a basic understanding of cancer biology and its translation into efficient therapies

I Tinhofer, D Braunholz, K Klinghammer - Cancers of the Head & Neck, 2020 - Springer
Comprehensive molecular characterization of head and neck squamous cell carcinoma
(HNSCC) has led to the identification of distinct molecular subgroups with fundamental …

[HTML][HTML] Density of CD3+ and CD8+ cells in gingivo-buccal oral squamous cell carcinoma is associated with lymph node metastases and survival

G Mukherjee, S Bag, P Chakraborty, D Dey, S Roy… - PloS one, 2020 - journals.plos.org
The tumor immune microenvironment is emerging as a critical player in predicting cancer
prognosis and response to therapies. However, the prognostic value of tumor-infiltrating …

[HTML][HTML] Construction and analysis of a lncRNA-miRNA-mRNA network based on competitive endogenous RNA reveal functional lncRNAs in oral cancer

J Yin, X Zeng, Z Ai, M Yu, Y Wu, S Li - BMC medical genomics, 2020 - Springer
Background A growing evidence suggests that long non-coding RNAs (lncRNAs) can
function as a microRNA (miRNA) sponge in various diseases including oral cancer …