[HTML][HTML] Recent insights into neuromuscular junction biology in Duchenne muscular dystrophy: Impacts, challenges, and opportunities
SY Ng, V Ljubicic - EBioMedicine, 2020 - thelancet.com
Duchenne muscular dystrophy (DMD) is the most common and relentless form of muscular
dystrophy. The pleiotropic effects of dystrophin deficiency include remarkable impacts on …
dystrophy. The pleiotropic effects of dystrophin deficiency include remarkable impacts on …
'Fragmentation'of NMJs: a sign of degeneration or regeneration? A long journey with many junctions
CR Slater - Neuroscience, 2020 - Elsevier
Mammalian neuromuscular junctions (NMJs) often consist of curved bands of synaptic
contact, about 3–6 μm wide, which resemble pretzels. This contrasts with the NMJs of most …
contact, about 3–6 μm wide, which resemble pretzels. This contrasts with the NMJs of most …
Targeting RAGE prevents muscle wasting and prolongs survival in cancer cachexia
S Chiappalupi, G Sorci, A Vukasinovic… - Journal of cachexia …, 2020 - Wiley Online Library
Background Cachexia, a multifactorial syndrome affecting more than 50% of patients with
advanced cancer and responsible for~ 20% of cancer‐associated deaths, is still a poorly …
advanced cancer and responsible for~ 20% of cancer‐associated deaths, is still a poorly …
[HTML][HTML] Lifetime analysis of mdx skeletal muscle reveals a progressive pathology that leads to myofiber loss
RT Massopust, YI Lee, AL Pritchard, VKM Nguyen… - Scientific Reports, 2020 - nature.com
The muscular dystrophy X-linked mouse (mdx) is the most commonly used preclinical model
for Duchenne muscular dystrophy. Although disease progression in the mouse does not …
for Duchenne muscular dystrophy. Although disease progression in the mouse does not …
Alterations of neuromuscular junctions in Duchenne muscular dystrophy
RM Lovering, SR Iyer, B Edwards, KE Davies - Neuroscience letters, 2020 - Elsevier
The focus of this review is on Duchenne muscular dystrophy (DMD), which is caused by the
absence of the protein dystrophin and is characterized as a neuromuscular disease in which …
absence of the protein dystrophin and is characterized as a neuromuscular disease in which …
Evaluation of a conducting elastomeric composite material for intramuscular electrode application
Electrical stimulation of the muscle has been proven efficacious in preventing atrophy and/or
reanimating paralyzed muscles. Intramuscular electrodes made from metals have …
reanimating paralyzed muscles. Intramuscular electrodes made from metals have …
[HTML][HTML] Plasmalemma function is rapidly restored in mdx muscle after eccentric contractions
CW Baumann, GL Warren, DA Lowe - Medicine and science in …, 2020 - ncbi.nlm.nih.gov
Purpose: Muscle that lacks dystrophin, as in the mdx mouse, has a heightened sensitivity to
eccentric (ECC) contraction-induced strength loss, but an enhanced rate of recovery …
eccentric (ECC) contraction-induced strength loss, but an enhanced rate of recovery …
Glycerophospholipid profile alterations are associated with murine muscle‐wasting phenotype
Introduction Phospholipids are essential components of cellular membranes and are closely
associated with cellular functions, but relationships involving skeletal muscle phospholipid …
associated with cellular functions, but relationships involving skeletal muscle phospholipid …
Examination of the human motor endplate after brachial plexus injury with two‐photon microscopy
Introduction After traumatic nerve injury, neuromuscular junction remodeling plays a key role
in determining functional outcomes. Immunohistochemical analyses of denervated muscle …
in determining functional outcomes. Immunohistochemical analyses of denervated muscle …
Acute contraction-induced strength loss, muscle inexcitability and recovery after exercise in males with Duchenne muscular dystrophy
JP Trost - 2020 - search.proquest.com
This dissertation had three objectives with the overall goal to explore contraction-induced
strength loss and recovery in males with Duchenne muscular dystrophy (DMD) specifically …
strength loss and recovery in males with Duchenne muscular dystrophy (DMD) specifically …